Search for dissertations about: "Yersinia"

Showing result 21 - 25 of 55 swedish dissertations containing the word Yersinia.

  1. 21. Diagnostic PCR for the Detection of Yersinia enterocolitica and Salmonella in the Food-Chain: Reliability of PCR Performance

    University dissertation from Applied Microbiology (LTH)

    Author : Rickard Knutsson; [2001]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Livsmedelsteknik; Food and drink technology; Kemiteknik och kemisk teknologi; Chemical technology and engineering; real-time PCR; YPCE medium; Enrichment PCR; DNA polymerases; PCR inhibitors; pre-PCR processing; Salmonella; Diagnostic PCR; Yersinia enterocolitica; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : This thesis deals with the methodological advances of diagnostic PCR including reliability of PCR and pre-PCR processing of food and feed samples. Diagnostic PCR has been greatly improved by the introduction of the second generation of PCR, so-called real-time PCR. READ MORE

  2. 22. Regulation of the multi-functional protein YscU in assembly of the Yersinia type III secretion injectisome

    University dissertation from Umeå : Umeå University

    Author : Ho Ngoc Hoang Oanh; Magnus Wolf-Watz; Anna Linusson Jonsson; Maria Sunnerhagen; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system T3SS ; injectisome; Yersinia pseudotuberculosis; inhibitors; Yops; YscU; YscP; YscI; disorder-to-order transition; nuclear magnetic resonance NMR ; circular dichroism CD ; isothermal titration calorimetry ITC ; biologisk kemi; biological chemistry;

    Abstract : Yersinia pseudotuberculosis is a Gram-negative zoonotic pathogenic bacterium causing gastroenteritis in human and animals. It shares a conserved virulence plasmid encoding for a needle-like secretion machinery, or type III secretion system, which can be found in other pathogenic Gram-negative bacteria. READ MORE

  3. 23. Controlling virulence in Yersinia pseudotuberculosis through accumulation of phosphorylated CpxR

    University dissertation from Umeå : Umeå university

    Author : Edvin Thanikkal; Matthew Francis; Andrew Darwin; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Y. pseudotuberculosis; CpxA; CpxR; invasin; RovA; RovM; T3SS; virulence; transcriptional regulation; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Abstract : Like many Gram-negative bacteria, the food-borne pathogen Yersinia pseudotuberculosis harbours different regulatory mechanisms to maintain an intact bacterial envelope especially during exposure to extracytoplasmic stress (ECS). The CpxA-CpxR two component regulatory system is one such ECS-responsive regulatory mechanism. READ MORE

  4. 24. Role of YopE and LcrH in effector translocation, HeLa cell cytotoxicity and virulence

    University dissertation from Umeå : Molekylärbiologi (Teknisk-naturvetenskaplig fakultet)

    Author : Margareta Aili; Roland Rosqvist; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; bacterial pathogenesis; YopE; LcrH; virulence; effector translocation; type III secretion; regulation; ODONTOLOGY Cell and molecular biology; ODONTOLOGI Cell- och molekylärbiologi;

    Abstract : In order to establish an extra-cellular infection the gram-negative bacteria Yersinia pseudotuberculosis uses a type III secretion system (T3SS) to translocate a set of anti-host effectors into eukaryotic cells. The toxins disrupt signalling pathways important for phagocytosis, cytokine production and cell survival. READ MORE

  5. 25. Small Molecules as Tools in Biological Chemistry Effects of Synthetic and Natural Products on the Type III Secretion System

    University dissertation from Umeå : Umeå universitet

    Author : Caroline E. Zetterström; Mikael Elofsson; Samuel I. Miller; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type III secretion; salicylidene acylhydrazide; virulence-blocker; virulence; inhibitor; target identification; neohopeaphenol A; Yersinia pseudotuberculosis; Pseudomonas aeruginosa; Escherichia coli; biologisk kemi; biological chemistry;

    Abstract : The increasing use of antibiotics has led to a huge problem for society, as some bacteria have developed resistance towards many of the antibiotics currently available. To help find solutions to this problem we studied small molecules that inhibit bacterial virulence, the ability to cause disease. READ MORE