Search for dissertations about: "Yiwen Jiang"

Found 1 swedish dissertation containing the words Yiwen Jiang.

2. 1. Interplay Between Cell of Origin and Oncogenic Activation in Glioma

   Author : Yiwen Jiang; Lene Uhrbom; Anders Persson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; PDGF; cell of origin; Sox5; glioma initiating cells; Oncology; Onkologi;

   Abstract : Glioma is the most frequent primary tumor of the central nervous system. By using the RCAS/tv-a mouse glioma model, we have studied mechanisms controlling glioma development and the effect of cell of origin on these processes.SOX5 was identified as a brain tumor locus in a retroviral insertional mutagenesis screen of PDGF-B induced mouse gliomas. READ MORE