Search for dissertations about: "Ylva Böttiger"

Found 3 swedish dissertations containing the words Ylva Böttiger.

  2. 1. Metabolic drug interactions in man : methodological aspects on in vivo studies

    Author : Ylva Böttiger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : drug interactions; drug metabolism; cytochrome P450; therapeutic drug monitoring; omeprazole; ketoconazole; tolterodine; ropivacaine; sirolimus; diltiazem; lamotrigine; humans;

    Abstract : The aim of this thesis was to investigate methodological aspects on in vivo metabolic drug interaction studies in man. Five pharmacokinetic studies in healthy persons or patients are presented. Together, they represent a set of model studies to evaluate the occurrence of, and extent of metabolic drug interactions in vivo. READ MORE

  4. 2. Therapeutic Drug Monitoring in Psychiatry : Some aspects of utility in clinical practice and research

    Author : Maria Dolores Chermá Yeste; Finn Bengtsson; Johan Ahlner; Ylva Böttiger; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TDM; psychoactive drug; pharmacokinetics; pharmacogenetics; naturalistic; elderly; child; Clinical pharmacology; Klinisk farmakologi;

    Abstract : Background and objectives: Several new psychoactive drugs for the treatment of psychiatric disorders have been introduced onto the market since the late 1980s. Basic aspects of pharmacodynamics and pharmacokinetics (PK) are investigated before approval for general prescription. READ MORE

  5. 3. Potentially inappropriate drug treatment among older people with cognitive impairment

    Author : Eva Sönnerstam; Maria Gustafsson; Maria Sjölander; Hugo Lövheim; Ylva Böttiger; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Older people; major neurocognitive disorder; cognitive impairment; potentially inappropriate medications; drug-drug interactions; renal function; adverse drug reactions; nursing homes; time trends; Clinical Pharmacology; klinisk farmakologi;

    Abstract : Background: The aging process contributes to alterations in organ systems, which lead to an increased risk for chronic conditions. Drug treatment is an important strategy in the management of chronic conditions; however, pharmacokinetic and pharmacodynamic alterations contribute to increased sensitivity to drug effects. READ MORE