Search for dissertations about: "YopH"

Showing result 6 - 10 of 10 swedish dissertations containing the word YopH.

  2. 6. Yersinia-phagocyte interactions during early infection

    Author : Linda Westermark; Maria Fällman; Joan Mecsas; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; dendritic cell; macrophage; neutrophil; T3SS; Infectious Diseases; infektionssjukdomar;

    Abstract : Pathogenic Gram-negative Yersinia species preferentially target and inactivate phagocytic cells of the innate immune defense by translocation of effector Yersinia outer proteins (Yops) into the cells via a type III secretion system. This indicates that inactivation and avoidance of the early innate immune response is an efficient way for Yersinia species to avoid elimination and to cause diseases ranging from mild gastroenteritis (Y. READ MORE

  4. 7. Temperature-inducible and calcium-regulated proteins encoded by the virulence plasmid of Yersinia

    Author : Ingrid Bölin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; virulence plasmid; gene products; regulation; calcium; temperature; outer membrane proteins;

    Abstract : The pathogenic members of the genus Yersinia, Y. pseudotuberculosis, Y. pestis and Y. enterocolitica are transmitted from animals to man and may give rise to disease with a variety of symptoms. READ MORE

  5. 8. Interaction between gastric pathogen Helicobacter pylori and host cells

    Author : Bin Su; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Helicobacter pylori; receptors; Lewis blood group antigen; MCP; integrin and signals;

    Abstract : H. pylori plays a causative role in the pathogenesis of gastritis, gastric atrophy, gastric and duodenal ulcer, and is believed to predispose to gastric adenocarcinoma as well as low-grade B-cell lymphoma. Lewisb (Leb) blood group antigen is a receptor for Leb adhesin-positive H. pylori strains. READ MORE

  6. 9. Host-pathogen interactions during Campylobacter and Yersinia infections

    Author : Nayyer Taheri; Anna Fahlgren; Maria Fällman; Sun Nyunt Wai; Elena Vikström; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Campylobacter jejuni; Yersinia pseudotuberculosis; OMV; bile; temperature; proteomic;

    Abstract : The innate immune system is known for protecting the host against invading pathogens, for instance enteropathogens infecting the gastrointestinal tract. The production of e.g. antimicrobial peptides, cytokines, and chemokines by innate immune cells and intestinal epithelial cells contribute to bacterial clearance. READ MORE

  7. 10. Multiple functions of YopN in the Yersinia pseudotuberculosis type III secretion system : from regulation to in vivo infection

    Author : Sarp Bamyaci; Åke Forsberg; Edouard Galyov; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system; Yersinia; YopN; virulence; phagocytosis; mouse infection; secretion kinetics;

    Abstract : The type 3 secretion systems (T3SSs) are virulence mechanisms used by various Gram-negative bacteria to overcome the host immunity. They are often target-cell contact induced and activated. Activation results in targeting of virulence effector substrates into host cells. READ MORE