Search for dissertations about: "Yumei Diao"

Found 1 swedish dissertation containing the words Yumei Diao.

2. 1. GLI1 modulation of the output of hedgehog signaling in human cancer

   Author : Yumei Diao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The Hedgehog (HH) signaling pathway has critical roles in embryonic development and tumorigenesis. Aberrant activation of HH signaling has been known to be involved in several types of malignant tumors. GLI1 is a transcription factor that acts not only as the terminal effector but also represents a pathway target gene, amplifying the HH signal. READ MORE