Search for dissertations about: "Zoledronate"
Showing result 1 - 5 of 7 swedish dissertations containing the word Zoledronate.
-
1. The Anabolic - Anti-catabolic Paradigm of Augmenting Skeletal Regeneration: A Bone Quality Perspective
Abstract : Successful fracture repair is a complex series of coordinated processes leading to regeneration of new bone to bridge the fracture site, remodelling of the newly formed bone and restoration of skeletal function. Disruption of these processes occurs in approximately 10% of all fractures and leads to delayed or failed healing requiring surgical interventions, increased complication rates, prolonged rehabilitation and high morbidity. READ MORE
-
2. Pharmacological manipulation of fracture healing and bone remodeling
Abstract : Drug treatment has been and will continue to be a successful method in modern medicine that can change the course of a disease. However, it is surprisingly seldom used in the more technically oriented orthopedic surgery. READ MORE
-
3. Allograft bone in hip revision: the effect of locally applied pharmacological treatment
Abstract : The clinical success of primary hip replacement is paramount but the need for revisions will continue to increase due to the increasing number of operated individuals. In Sweden, the number of hip revisions in 2012 exceeded 2,300. During implant loosening, some of the bone in the femur is lost, which can make the revision more difficult. READ MORE
-
4. Enhancing bone healing through concurrent anabolic- and anti-catabolic pharmacological treatment
Abstract : Most fractures heal uneventfully but some evolve into nonunions. Autologous bone graft is the gold standard for stimulating healing. However, donor site morbidity, and limited graft supply make alternatives interesting. Bone Morphogenetic Proteins, BMPs, are growth factors involved in bone signaling. READ MORE
-
5. Bisphosphonates and implants in the jaw bone
Abstract : Insertion of metal implants in bone is one of the commonest of all surgical procedures. The success of these operations is dependent on the fixation of the implants, which, in turn, depends on the strength of the bone that holds them. READ MORE