Search for dissertations about: "Zuzana Hassan"

Found 1 swedish dissertation containing the words Zuzana Hassan.

2. 1. Studies on mechanisms of busulphan cytotoxicity and pharmacokinetics : with special reference to liposomal busulphan

   Author : Zuzana Hassan; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Busulphan is an alkylating agent currently used in conditioning regimen prior to stem cell transplantation (SCT). High dose therapy with busulphan has been shown to contribute to transplantation-related toxicities, such as veno-occlusive disease (VOID) and interstitial pneumonia, Previous pharmacodynamic studies have attempted to define a target systemic exposure to busulphan, and thresholds for different side effects. READ MORE