Search for dissertations about: "a - ketoglutarate"

Showing result 1 - 5 of 15 swedish dissertations containing the words a - ketoglutarate.

  2. 1. Islet Transplantation a Technical Challenge : Studies on Human Pancreas Preservation and Enzymatic Digestion

    Author : José Caballero-Corbalán; Olle Korsgren; Daniel Brandhorst; Ralf Segersvärd; Federico Bertuzzi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet transplantation; Human islet isolation; Pancreas preservation; Two-layer method; Perfluorocarbon; Cold storage; Cold ischemia; University of Wisconsin solution; Histidine-tryptophan-ketoglutarate; HTK; Pancreas preservation; Prediction; Collagenase; Trasplante de islotes; Aislamiento de islotes; Preservación del pancreas; Método de las dos capas; Colagenasa; Solución de Wisconsin; HTK; Histidina-triptófano-ketoglutarato; Predicción; Endocrinology; Endokrinologi; Transplantation surgery; Transplantationskirurgi; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Cellforskning; Cell Research; Klinisk immunologi; Clinical Immunology;

    Abstract : Islet transplantation has found its niche in diabetes treatment. It has contributed to a better quality of life and better glycemic control of patients with diabetes suffering from severe hypoglycemia that are not eligible for vascularized pancreas transplantation. Islet isolation is a technically challenging procedure. READ MORE

  4. 2. Mitochondrial Energy Metabolism : Kgd4 is a novel subunit of the α-ketoglutarate dehydrogenase complex

    Author : Manfred Heublein; Martin Ott; Flavia Fontanesi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; α-ketoglutarate dehydrogenase; Kgd4; Krebs cycle; Biochemistry; biokemi;

    Abstract : Mitochondria are essential organelles of eukaryotic cells and are responsible for their energy metabolism. The citric acid cycle, a chain of redox reactions in the mitochondrial matrix, is a central metabolic hub. READ MORE

  5. 3. Metabolic intervention during blood cardioplegia. Clinical studies in coronary surgery and heart transplantation

    Author : Ulf Kjellman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac surgery; heart transplantation; oxygen extraction; substrate metabolism; predictors of ischemic injuries; a - ketoglutarate; insulin;

    Abstract : Myocardial ischemia and injury (infarction) during open heart surgery and heart transplantation is a problem in spite of the fact that it is a safe procedure today. The myocardial substrate metabolism is well investigated before and after the cardioplegic period but little knowledge exists about the myocardial metabolic changes during cardioplegia. READ MORE

  6. 4. Exploring Yeast as a Cell Factory for the Production of Carboxylic Acids and Derivatives

    Author : Diogo Portugal-Nunes; Teknisk mikrobiologi; []
    Keywords : Saccharomyces cerevisiae; Poly-3-D-hydroxybutyrate PHB ; Carboxylic acids; Alpha-ketoglutarate AKG ; Xylose assimilation; Weimberg pathway;

    Abstract : Baker’s yeast, Saccharomyces cerevisiae, is a promising cell factory for the sustainable utilization of renewable resources for the formation of products with commercial value. Among these, poly-3-D-hydroxybutyrate (PHB) is an extensively studied biopolymer naturally accumulated in some bacteria and archaea species through the formation of carbon granules. READ MORE

  7. 5. Structure and Biogenesis of Membrane Proteins

    Author : Mama Ndi; Martin Ott; Alexander Kastaniotis; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cbp3; cytochrome b; respiratory complex III; alternative translation initiation and sodium proton exchange; Biochemistry; biokemi;

    Abstract : Membrane proteins make up about one-third of the cellular proteome. The diverse roles that membrane proteins have in cells include major life-sustaining processes, making them major drug targets. READ MORE