Search for dissertations about: "a1-microglobulin"
Found 4 swedish dissertations containing the word a1-microglobulin.
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1. On new and current treatments for Diamond-Blackfan anemia
Abstract : Diamond-Blackfan anemia (DBA) is a rare congenital disease where the patients suffer from macrocytic anemia due to reduced numbers of erythroid precursors in the bone marrow. Most patients carry mutations in ribosomal proteins, such as ribosomal protein S19 (RPS19), which causes deficient ribosome biogenesis and affects protein translation. READ MORE
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2. Preeclampsia - A cardiovascular risk factor
Abstract : .... READ MORE
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3. Structural and evolutionary studies of a lipocalin: the alpha1-microglobulin protein and its gene
Abstract : a1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indications of the presence of a receptor for a1-microglobulin on T-lymphocytes. READ MORE
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4. Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant
Abstract : This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. READ MORE