Search for dissertations about: "abnormal sex differentiation"

Found 3 swedish dissertations containing the words abnormal sex differentiation.

  2. 1. Studies of androgen receptor gene mutations in patients phenotypically ranging from complete androgen insensitivity to men with preserved fertility

    Author : Yvonne Lundberg Giwercman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : androgen insensitivity; androgen receptor; mutations; genetic diagnostics; abnormal sex differentiation; infertility;

    Abstract : The androgen insensitivity syndrome (AIS) is the single most common cause of male pseudohermaphroditism, i. e., deficient masculinization which is not explained by disturbed testis development. In its most severe form it affects at least 1/20 000 newborn 46, XY males. READ MORE

  4. 2. Adrenocortical tumors : Diagnosis, growth regulation and treatment

    Author : Carin Backlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Monoclonal antibodies generated by immunization with human adrenocortical cells reacted with the normal adrenal cortex, adrenocortical adenomas and carcinomas, but failed to stain a variety of normal tissues, renal cell carcinoma, and pheocromocytomas. The antibodies can be used to improve histological diagnosis and characterization of human adrenal lesions, and possibly for scintigraphic detection. READ MORE

  5. 3. Exploring the Grey Zone between Type 1 and Type 2 Diabetes

    Author : Ekaterine Bakhtadze; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring at least for 6 month after diagnosis. READ MORE