Search for dissertations about: "abnormalities in breast cancer"

Showing result 1 - 5 of 12 swedish dissertations containing the words abnormalities in breast cancer.

  2. 1. Predictors of Lymph Node Metastasis in Primary Breast Cancer - Risk Models for Tailored Axillary Management

    Author : Looket Dihge; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; Axillary lymph node dissection; Sentinel lymph node biopsy; Ultrasonography; Nomogram; Artificial neural network; Gene Expression; Prediction model;

    Abstract : Most patients with breast cancer present with low-risk tumors, node-negative disease, and excellent prognosis. For these patients, routine axillary nodal staging by sentinel lymph node biopsy (SLNB) has no therapeutic benefit. For patients with limited sentinel lymph node metastasis, completion axillary nodal dissection is controversial. READ MORE

  4. 2. Cytogenetic studies of benign breast lesions

    Author : Catarina Lundin; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; cancer risk; breast cancer; phyllodes tumor; papilloma; fibroadenoma; prophylactic mastectomies; fibrocystic lesions; Cytogenetics; chromosomes; Klinisk genetik; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In the present thesis benign breast lesions of various histologies, i.e. READ MORE

  5. 3. Cardiac and pulmonary side-effects of radiotherapy in early breast cancer

    Author : Ulla Blom Goldman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : breast cancer;

    Abstract : The purpose of this thesis was to study early and late side-effects to lung and heart in adjuvant locoregionalradiation therapy (LRRT) of early breast cancer (BC). Papers I-III were intervention studies aiming to reduce symptomatic/ radiological pneumonitis and functional changes after LRRT by applyingthe ipsilateral lung dose volume constraint V20 ≤ 30 %. READ MORE

  6. 4. Tumor Suppressor function of the deubiquitinating enzyme BAP1 and its substrate gamma-tubulin In regulation of cell cycle and genome stability

    Author : Reihaneh Zarrizi; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In normal cells, the cell cycle is controlled by a complex series of signalling pathways by which a cell grows, replicates its DNA and divides. The critical task of the cell cycle is to ensure that DNA is faithfully replicated and that identical chromosomal copies are distributed equally to two daughter cells during mitosis with the help of the mitotic spindle. READ MORE

  7. 5. PAK4 signaling in development and cancer

    Author : Tânia Costa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Our understanding of cancer biology has been evolving rapidly shaped by groundbreaking discoveries. We now understand that cancer is not one disease but many, and that tumors are not foreign objects in the human body but rather the result of changes in the previously normal tissues and organs. READ MORE