Search for dissertations about: "abortive proliferation"

Found 1 swedish dissertation containing the words abortive proliferation.

2. 1. Development of a protein-free fed-batch process for NS0 cells: studies on regulation of proliferation

   Author : Erika Spens; Lena Häggström; Jean-Louis Goergen; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NS0 myeloma cells; protein-free medium; fed-batch; conditioned medium; autocrine growth factors; abortive proliferation; protease activity; aprotinin; gp130; Bioengineering; Bioteknik;

   Abstract : The overall objective of this study was to investigate how NS0 cell proliferation is regulated in protein-free media. The hypothesis was that during the adaptation to growth factor-free media, animal cell lines start to produce their own autocrine growth factors to support proliferation, and after some time in a culture the effects of these factors are lost which results in cessation of proliferation. READ MORE