Search for dissertations about: "absolute quantification"

Showing result 1 - 5 of 51 swedish dissertations containing the words absolute quantification.

  2. 1. Multiplexed absolute quantification of blood plasma proteins using targeted proteomics

    Author : David Kotol; Mathias Uhlén; Edfors Fredrik; Roman Zubarev; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; targeted proteomics; stable isotope standards; recombinant protein standards; absolute quantification; blood plasma; multiplex analysis; plasma profiling; Biotechnology; Bioteknologi;

    Abstract : Proteins are the molecular building blocks of all living organisms. They are the functioning actors in metabolism and communication, and they give specific architecture and purpose to all tissues. Their abundance is dynamic and can be interpreted and associated to different physiological states or diseases. READ MORE

  4. 2. Image Processing for Quantitative Scintillation-Camera Imaging. Application to Radionuclide Therapy

    Author : Katarina Sjögreen Gleisner; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; 131-I; Clinical physics; SPECT; conjugate-view; volume quantification; activity quantification; image registration; image segmentation; medicinsk instrumentering; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

    Abstract : Individual-based determinations of the absorbed dose in radionuclide therapy largely rely on absolute measurement of the activity distribution and its redistribution over time. Scintillation-camera imaging is the most commonly employed measuring technique, applied in planar or SPECT mode, sometimes in combination with structural images from CT. READ MORE

  5. 3. High-throughput protein analysis using mass spectrometry-based methods

    Author : Tove Boström; Sophia Hober; Thomas Laurell; Ole N. Jensen; KTH; []
    Keywords : Proteomics; mass spectrometry; affinity proteomics; immunoenrichment; immunoprecipitation; IMAC; screening; protein production; protein purification; ISET; quantification; SILAC; stable isotope standard; antibody validation; Bioteknologi; Biotechnology;

    Abstract : In the field of proteomics, proteins are analyzed and quantified in high numbers. Protein analysis is of great importance and can for example generate information regarding protein function and involvement in disease. Different strategies for protein analysis and quan- tification have emerged, suitable for different applications. READ MORE

  6. 4. Assessment of attenuation correction methods for quantitative neuro-PET/MR

    Author : Joao M. Sousa; Mark Lubberink; Lieuwe Appel; Håkan Ahlström; Mathias Engström; Ivo Rausch; Radiologi Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; MRI; attenuation correction; 68Ge transmission; quantification; 11C-PE2I; MRAC; DAT; CBF; Medicinsk radiofysik; Medical Radiophysics;

    Abstract : Hybrid PET/magnetic resonance (MR) can provide physiological, functional, and structural information simultaneously, facilitating research in neurological disorders. For quantitative PET, correction for photon attenuation (AC) is necessary. READ MORE

  7. 5. Development of novel affinity enrichment strategies for clinical applications using selected reaction monitoring

    Author : Andreas Hober; Mathias Uhlén; Fredrik Edfors; Björn Forsström; Johan Malmström; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; proteomics; mass spectrometry; selected reaction monitoring; absolute quantification; antibody validation; precision medicine; Biotechnology; Bioteknologi;

    Abstract : Proteins are key components of any living organism and an essential part of life itself. They can provide cells with structure and perform life-sustaining intracellular reactions. As organisms grow more complex, this task expands even further. READ MORE