Search for dissertations about: "acidic patch"

Found 5 swedish dissertations containing the words acidic patch.

2. 1. Allosteric control of ALC1-catalyzed nucleosome remodeling

   Author : Laura C. Lehmann; Sebastian Deindl; Stefan D. Knight; Felix Müller-Planitz; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ALC1; CHD1L; ATP-dependent chromatin remodeling; nucleosome; allosteric regulation; autoinhibition; macro domain; PARP; ADP-ribosylation; DNA damage; acidic patch; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

   Abstract : The genetic information of eukaryotic cells is packaged inside the nucleus as chromatin. This packaging restricts access to the DNA and therefore represents a barrier for processes such as DNA replication, repair, and gene expression. READ MORE

4. 2. Histochemical, biochemical and electrophysiological studies on dorsal root ganglion cultures : focusing on galanin, neuropeptide Y and glutamate

   Author : Nora Kerekes; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acute and long-term DRG cultures; aFGF; BDNF; bFGF; bradykinin; excitability; galanin; glutamate; leukemia inhibitory factor; neuropeptide Y; : NGF; regeneration; whole cell patch clamp.;

   Abstract : Galanin (Gal) and neuropeptide Y (NPY) are two peptides, which are strongly up- regulated in a population of dorsal root ganglion (DRG) neurons after peripheral nerve injury (axotomy). Both peptides may be involved in the control of pain sensation, especially after nerve injury (neuropathic pain). READ MORE

5. 3. Studies on spinach plastocyanin and mutants : Expression in Escherichia coli, folding and function

   Author : Mikael Ejdebäck; Örjan Hansson; Miguel A. De la Rosa; Göteborgs Universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; plastocyanin; electron transfer; copper; protein-protein interactions; protein expression; folding; site-directed mutagenesis; NMR; Naturvetenskap; Natural sciences;

   Abstract : Photosynthesis is a process in which photons from sunlight excite chlorophylls in the thylakoid membranes of plants, algae and cyanobacteria. The photo-oxidised reaction centre chlorophyll P700 is re-reduced by an electron transferred from the soluble, blue copper protein plastocyanin. READ MORE

6. 4. Molecular mechanisms underlying the activation of ALC1 nucleosome remodeling

   Author : Luka Bacic; Sebastian Deindl; Stefan D. Knight; Lari Lehtiö; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; ALC1; CHD1L; nucleosome; ADP-ribosylation; chromatin; remodeling; PARP1; HPF1; DNA damage; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

   Abstract : Packaging DNA into chromatin represses essential DNA-based processes, such as transcription, DNA replication, and repair. To change the accessibility of DNA, cells have evolved a set of enzymes referred to as chromatin remodelers that act on the basic repeat unit of chromatin,  the nucleosome. READ MORE

7. 5. Structural and functional studies of protein complexes involved in energy metabolism

   Author : Jens Berndtsson; Martin Ott; Irene Diaz-Moreno; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondria; metabolism; OXPHOS; yeast respiratory supercomplex; cytochrome c; coenzyme Q; pyruvate dehydrogenase complex; Biochemistry; biokemi;

   Abstract : Mitochondria are eukaryotic organelles with a multitude of functions including biosynthesis of molecules and cellular regulation. Most prominently though is their role in energy conversion which culminates with the production of ATP, the universal molecular unit of currency. READ MORE