Search for dissertations about: "acrR"

Found 1 swedish dissertation containing the word acrR.

  1. 1. Constraints on up-regulation of drug efflux in the evolution of ciprofloxacin resistance

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lisa Praski Alzrigat; Diarmaid Hughes; Fernando Baquero; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ciprofloxacin; antibiotic resistance; drug efflux; bacterial fitness; marR; acrR; marA; experimental evolution; Mikrobiologi; Microbiology;

    Abstract : The crucial role of antibiotics in modern medicine, in curing infections and enabling advanced medical procedures, is being threatened by the increasing frequency of resistant bacteria. Better understanding of the forces selecting resistance mutations could help develop strategies to optimize the use of antibiotics and slow the spread of resistance. READ MORE