Search for dissertations about: "actinomycin"

Showing result 1 - 5 of 11 swedish dissertations containing the word actinomycin.

  2. 1. Lipoprotein lipase : mechanism for adaptation of activity to the nutritional state

    Author : Gengshu Wu; Thomas Olivecrona; Gunilla Olivecrona; Peter Nisson-Ehle; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; adipose tissue; heparin; extracellular; nutrition; turnover; actinomycin; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Lipoprotein lipase (LPL) is an enzyme to hydrolyze triglycerides in lipoproteins and thereby make the fatty acids available for cellular metabolic reactions. Short-term fasting down-regulates LPL activity in adipose tissue. This regulation is through post-translational mechanism. READ MORE

  4. 2. Single cell analysis of checkpoints in G1

    Author : Hanna-Stina Martinsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cell cycle; restriction point; cyclin D; pRb; rRNA synthesis; cell growth; attachment;

    Abstract : It is becoming evident that defective cell cycle regulation is an important property of the cancer cell. The restriction point (R), a G1 checkpoint after which cell cycle progression becomes independent of extracellular growth factors, is often aberrant in cancer cells. READ MORE

  5. 3. Molecular characterization of apoptosis in B-cell chronic lymphocytic leukemia

    Author : Anna Olsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : B-CLL; apoptosis; TRAIL; FLIP; Bmf; Bfl-1;

    Abstract : B-cell chronic lymphocytic leukemia (B-CLL), characterized by an accumulation of monclonal B cells, is the most common adult leukemia in the Western world. Defective apoptosis is considered to contribute to cell accumulation, disease progression and resistance to therapy in BCLL. READ MORE

  6. 4. In vitro studies on the potential immunosuppressive and antitumor effects of antidepressants : induction of apoptosis in human T-cells and a myeloid leukemia cell line

    Author : Zhenlei Xia; Tom Cotter; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Antidepressants are widely used in treating depressive disorders. It has been demonstrated that several components of the immune system may be activated in the acute clinical stage of major depression and that such activation may play a role in the onset of depressive symptoms. READ MORE

  7. 5. Metabolism of articular cartilage proteoglycans in vitro : effects of synovial membrane products and mechanical pressure

    Author : Agneta Klämfeldt; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Articular cartilage; Proteoglycan metabolism; Synovial membrane products; Mechanical stress; Indom ethacin; Glucocorticoids; Prostaglandins; Osteoarthritis; Rheumatoid arthritis;

    Abstract : The effect of synovial membrane products and mechanical pressure upon the metabolism of articular cartilage proteoglycans has been studied in vitro. The degradation of cartilage proteoglycans was studied in an organ culture system and measured as the release of [35S ] sulphate from prelabelled cartilage. READ MORE