Search for dissertations about: "activator protein-1"

Showing result 11 - 15 of 28 swedish dissertations containing the words activator protein-1.

  2. 11. Activation, adhesion and motility of B lymphocytes in health and disease

    Author : Natalija Gerasimcik; Eva Severinson; Victor Tybulewicz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; B cells; activation; motility; IL-4; EBV; Dock10; Cdc42; Rac1 and Rac2; immunologi; Immunology;

    Abstract : B cells can be activated by T cell-dependent stimuli, such as CD40 ligation and cytokines, which induce extensive proliferation, class switch recombination and somatic hypermutation.Epstein-Barr virus (EBV) can also induce B cell activation by mimicking T cell help through its main oncoprotein, latent membrane protein 1 (LMP-1). READ MORE

  4. 12. Coagulation, fibrinolysis and inflammation in open surgery for infrarenal abdominal aortic aneurysm

    Author : Anders Holmberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Abdominal aortic aneurysm; blood coagulation; fibrinolysis; cytokines; leucocytes; flow cytometry; chemotaxis; lactoferrin; myeloperoxidase; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Elective repair of infrarenal abdominal aortic aneurysm (AAA) carries a mortality of 4-8% and there is a substantial incidence of serious non-lethal complications. During surgery there is a situation of relative ischaemia and subsequent reperfusion of the lower part of the body. READ MORE

  5. 13. Studies on vascular remodeling in acute coronary artery disease

    Author : Fei Chen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherosclerosis; unstable angina; matrix metalloproteinase; apoptosis; angiogenesis; remodeling;

    Abstract : Atherosclerosis is an arterial disease, characterized by endothelial dysfunction, vascular inflammation, and lipid accumulation in the vessel wall. Unstable coronary syndroms may be initiated by rupture of the atherosclerotic plaque, which may be caused by activation of matrix metalloproteinases (MMPs), apoptosis and angiogenesis. READ MORE

  6. 14. Effects of ethanol on the expression of immediate-early genes in nerve cells

    Author : Wei-Qun Ding; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroadaptation; the central nervous system; AP-1; junD; junB; c-jun; fosB; c-fos; neuroblastoma SH-SY5Y; ethanol; immediate-early genes; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : Immediate-early genes of the fos and jun families encode proteins that dimerize to form a complex of activator protein 1 and regulate the expression of a number of genes in the nervous system. Ethanol has previously been shown to induce alterations in expression of fos and jun genes in the brain. READ MORE

  7. 15. Modulators of UCP1-dependent thermogenesis : Glucocorticoids, diet and novel research models

    Author : Ineke H. N. Luijten; Jan Nedergaard; Onno Meijer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; brown adipose tissue; UCP1; glucocorticoids; diet-induced thermogenesis; obesity; physiology; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The activation and recruitment of brown adipose tissue (BAT) thermogenesis has been put forward as a promising strategy to reduce the disease burden of obesity and obesity-related diseases. Heat production by BAT can be attributed to the tissue-specific mitochondrial uncoupling protein 1 (UCP1). READ MORE