Search for dissertations about: "activator protein-1"
Showing result 21 - 25 of 28 swedish dissertations containing the words activator protein-1.
-
21. Effects of hypoxia on macrophage function in atherosclerosis
Abstract : Atherosclerosis is a complex disease, which affects large and medium sized arteries and is characterized by an arterial wall thickening. A constant supply of oxygen is needed to maintain cell functions in the atherosclerotic plaque. The oxygen distribution to the cells in the arterial wall depends on diffusion. READ MORE
-
22. Molecular aspects of WNT/Frizzled signalling in brain angiogenesis
Abstract : The family of WNT lipoglycoproteins consists of 19 secreted proteins that are important for multiple cellular processes including cell proliferation, migration and fate. WNTs induce signalling cascades by binding the seven transmembrane receptors named Frizzleds (FZDs) classified as G protein-coupled receptors (GPCRs). READ MORE
-
23. Pathophysiological mechanisms and clinical manifestations in primary Sjögren’s syndrome and Systemic lupus erythematosus (SLE)
Abstract : Primary Sjögren’s syndrome (pSS) is a systemic inflammatory autoimmune condition. The etiology of pSS is mainly unknown, but it has been suggested that environmental factors trigger an immune response in genetically susceptible individuals. READ MORE
-
24. Aspects on latency in HIV-1 infection
Abstract : The use of combination antiretroviral therapy (ART) has resulted in a substantial reduction in viremia, a rebound of CD4+ T-cells and increased survival for human immunodeficiency virus type 1 (HIV-1) infected individuals. Unfortunately, ART does not clear the infection or cure the individual from HIV-1. READ MORE
-
25. On the role of HMGB1 and IL-1 in tissue barrier defense
Abstract : The specialized epithelial surfaces of the lymphoepithelial tissue in the airways and the seminiferous epithelium of the testis are sites of host-environmental interaction at the same time as they serve important physiological functions in gas exchange and reproduction. The host response of a broken epithelial barrier requires rapid mechanisms to control the microflora and to prevent invasion of pathogens. READ MORE