Search for dissertations about: "activity of the solid phase"

Showing result 1 - 5 of 102 swedish dissertations containing the words activity of the solid phase.

  2. 1. Solid-liquid Phase Equilibria and Crystallization of Disubstituted Benzene Derivatives

    Author : Fredrik Nordström; Åke Rasmuson; Gerard Coquerel; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Salicylic acid; m-hydroxybenzoic acid; p-hydroxybenzoic acid; salicylamide; m-aminobenzoic acid; p-aminobenzoic acid; solubility; solid-liquid equilibria; thermodynamics; activity of the solid phase; ideal solubility; activity coefficient; van t Hoff enthalpy of solution; solid state; solution properties; metastable zone width; primary nucleation; nucleation kinetics; Chemical engineering; Kemiteknik;

    Abstract : The Ph.D. project compiled in this thesis has focused on the role of the solvent in solid-liquid phase equilibria and in nucleation kinetics. Six organic substances have been selected as model compounds, viz. READ MORE

  4. 2. Crystallization of Parabens : Thermodynamics, Nucleation and Processing

    Author : Yang Huaiyu; Åke Rasmuson; Joop ter Horst; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nucleation; Induction time; Interfacial energy; Ethyl paraben; Propyl paraben; Butyl paraben; Methanol; Ethanol; Propanol; Acetone; Ethyl acetate; Solubility; Thermodynamics; Activity; Activity coefficient; Liquid-liquid phase separation; Ternary phase diagram; Melting point; Boiling point; Polarity; Cooling crystallization; Sandwich crystal; Porous; Particle Vision and Measurement; Focused Beam Reflectance Method; Infrared Spectroscopy; Confocal Raman Microscopy; X-Ray Diffraction; Differential Scanning Calorimetry; SRA - E-Science SeRC ; SRA - E-vetenskap SeRC ;

    Abstract : In this work, the solubility of butyl paraben in 7 pure solvents and in 5 different ethanol-water mixtures has been determined from 1 ˚C to 50 ˚C. The solubility of ethyl paraben and propyl paraben in various solvents has been determined at 10 ˚C. READ MORE

  5. 3. Immobilization and Interaction of Biomolecules at the Solid-Liquid Interface : Applications to Solid-Phase Analytical Techniques

    Author : Ulf Jönsson; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein immobilization; silica; Immunoglobulins; Protein A; Fibronectin; chemical-vapour deposition; silane; ellipsometry; radiolabeling; contact-angle measurement; solid-phase analytical techniques;

    Abstract : The development of solid-phase-analytical techniques based on surface-concentration-measuring devices requires a stable and reproducible immobilization of biomolecules on well-characterized solid surfaces. This study reports on the immobilization of Immunoglobulin G, Protein A and Fibronectin on chemically modified silica surfaces. READ MORE

  6. 4. Methodological studies in solid phase synthesis : Linkers and applications of multi-component condensations

    Author : Mikael Erlandsson; Anders Undén; Thomas Norberg; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solid phase peptide synthesis; solid phase organic chemistry; linkers; self-scavenging; safety catch linker; cyclic peptides; reductive acidolysis; disulfides; reduction; metallic zinc; multi-component condensations; combinatorial chemistry; Neurochemistry; Neurokemi;

    Abstract : Solid phase synthesis has become an increasingly important tool in the synthesis of oligopolymers and small organic molecules. This thesis covers three important areas in the solid phase synthesis technique: linker strategies, reduction methods and novel routes to complex heterocycles. READ MORE

  7. 5. Engineering of the Ultra-stable Cystine Knot Framework of Microproteins : Design, Chemical Synthesis and Structural Studies

    Author : Teshome Leta Aboye; Ulf Göransson; Julio A. Camarero; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclotides; cystine knot; protein engineering; NMR; solid phase; disulfide rich; ultra-stable; microprotein; PHARMACY; FARMACI; Medicinal Chemistry; Läkemedelskemi;

    Abstract : Ultra-stable cystine knotted microproteins, in which two disulfides and their connecting backbones form a circle that is penetrated by the third disulfide bonds, have attracted high interest due to their resistance to degradation in vitro and potential for the development of peptide drugs. This thesis gives new insights into engineering of that framework of microproteins, including approaches to their chemical synthesis, backbone engineering, structural and biological evaluations. READ MORE