Search for dissertations about: "activity-dependent learning and memory"

Showing result 1 - 5 of 7 swedish dissertations containing the words activity-dependent learning and memory.

2. 1. Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides

   Author : Andreas Toft Sörensen; Experimentell Epilepsi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTP; synaptic plasticity; synaptic transmission; electrophysiology; Y5 receptor; Y2 receptor; neuropeptide Y NPY ; hippocampus; gene therapy; epilepsy; memory; activity-dependent release; volume transmission;

   Abstract : Intractable seizures and lack of effective antiepileptic drugs (AED) are severe and common conditions affecting many patients with epilepsy. Thus, there is an urgent need to develop new therapies in epilepsy. The search for novel treatments has identified several neuropeptide systems as potential targets for future therapeutic interventions. READ MORE

4. 2. NO PAIN, STILL GAIN- cross-modality development learning guided by spinal spontaneous activity

   Author : Alexandra Waldenström Ellervik; Neurofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; Neurology; neuropsychology; development; spinal cord; activity-dependent learning and memory; pain; somatosensory; neurophysiology;

   Abstract : Recent studies indicate that experience dependent mechanisms shape the pain system during the development. In view of that painful stimuli are rare during development it is not clear how this is accomplished. READ MORE

5. 3. Roles of SNAP-25 isoforms in activity-dependent long-term synaptic plasticity

   Author : Muhammad Irfan; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : SNARE proteins, SNAP-25, syntaxin 1A and VAMP2 constitute the functional units which join together to form the core SNARE complex. The SNARE complex carries out the vital function of membrane fusion of intracellular vesicles with plasma membranes, leading to the release of neurotransmitters in brain neuronal circuits and of hormones in endocrine glands. READ MORE

6. 4. Short- and long-term neuronal plasticity in hippocampal CA1 region of rat

   Author : Fen-Sheng Huang; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glutamate; hippocampus; plasticity; synapse; LTP; LTD; AMPA; NMDA;

   Abstract : The brain is highly plastic, displaying both short- and long-term changes, resulting from developmental processes as well as learning and memory. Moreover, short-term plasticity such as paired pulse facilitation and depression (PPF, PPD) have long been used to monitor the presynaptic versus postsynaptic changes occurring during more lasting processes such as long-term potentiation and depression (LTP, LTD). READ MORE

7. 5. Re-evaluation of the hypothesis that LTP has two temporal phases and that the late phase is protein synthesis-dependent

   Author : Abdul-Karim Abbas; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine;

   Abstract : Long-term potentiation (LTP) is an activity-dependent increase in synaptic efficacy that is most studied in the hippocampus and that is considered a cellular substrate for learning and memory. Accepting the belief that the durability (persistence in time) of LTP is analogical to long-standing store of hippocampus-dependent memories warrants the necessity for understanding the mechanisms underlying LTP stabilization. READ MORE