Search for dissertations about: "acute HIV-1 infection"

Showing result 1 - 5 of 20 swedish dissertations containing the words acute HIV-1 infection.

  2. 1. On HIV-1 infection in the central nervous system

    Author : Åsa Mellgren; Göteborgs universitet; []
    Keywords : HIV-1; antiretroviral therapy; cerebrospinal fluid; neurofilament protein; AIDS dementia complex; neuropsychological test;

    Abstract : HIV-1 (hereafter referred to as HIV) is a neurotropic virus that invades the central nervous system (CNS). The CNS is then susceptible to an acute infection and later to CNS opportunistic diseases and AIDS dementia complex (ADC). HIV does not infect the neurons, and neuropathogenesis is largely mediated by the immune system. READ MORE

  4. 2. Aspects of immune activation in HIV-1 infection

    Author : Piotr Nowak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : immune activation; HMGB1; PHI; HIV-1 LTR-transcription; cytokines; chemokines;

    Abstract : Abnormal immune system activation is central in HIV-1 pathogenesis leading to CD4+ T-cell depletion and inappropriate immune responses. Disease stage and HIV load strongly correlate with the immune activation level which decreases under antiretroviral therapy (ART). READ MORE

  5. 3. Dynamics of HIV-1 infection within and between hosts

    Author : Jamirah Nazziwa; Systemvirologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; phylogenetics; acute HIV-1 infection; acute retroviral syndrome; innate immune responses; plasma proteome; intra-host HIV-1 evolution; mother-to-child HIV-1 transmission; disease progression;

    Abstract : .... READ MORE

  6. 4. Immunological properties of dendritic cells in HIV-1 infection

    Author : Karin Loré; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Dendritic cells; HIV-1; Cytokines; Chemokines; Co-stimulatory molecules; Apoptotic bodies; Lymphoid tissue;

    Abstract : Dendritic cells (DCs) capture antigens for intracellular processing to form MHC-peptide complexes involved in the generation of antigen specific T cell responses. After encountering microbes, DCs migrate from the periphery to the regional lymph nodes. READ MORE

  7. 5. Slow progression in HIV-1 infection : clinical, virological and immunological study

    Author : Christina Broström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV-1; PHI; prognosis; slow progression; LTNP; longitudinal; specific pattern; HIV-1 RNA; HIV-1 DNA; spontaneous decrease;

    Abstract : The aim of the present thesis was to study factors that could possibly influence the course of HIV-1 infection with special emphasis on slow progression of the disease. Clinical, virological and immunological parameters were evaluated. One important clinical factor for the outcome of HIV-1 infection was identified. READ MORE