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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

  2. 1. Occupational heat exposure and kidney disease - Studies on the role of heat stress in the Mesoamerican epidemic of Chronic Kidney Disease of non-traditional origin

    Author : Erik Hansson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat stress; heat strain; chronic kidney disease; acute kidney injury; occupational medicine;

    Abstract : This thesis examines the association between heat stress and kidney disease in Mesoamerica using different perspectives and methods. An ecologic study found that hot, sugarcane-cultivating regions had elevated chronic kidney disease (CKD) mortality. READ MORE

  4. 2. Acute inflammation in peritoneal dialysis. Experimental studies in rats. Characterization of regulatory mechanisms

    Author : Farhan Bazargani; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The predominant problems associated with peritoneal dialysis (PD) are ultrafiltration failure and peritonitis. PD maintains a state of intraperitoneal inflammation that affects the structure and function of the peritoneal membrane, potentially impairing ultrafiltration efficiency. READ MORE

  5. 3. Estimation of acute toxicity by using the differentiated neuronal progenitor C17.2 cell model

    Author : Jessica Lundqvist; Anna Forsby; Ann-Kristin Östlund Farrants; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurotoxicity; C17.2; cell membrane potential; Optimisation culture condition; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The authorities in Europe and United States request information regarding possible toxicity for substances that are produced in one tonne or more per year. Estimation of acute systemic toxicity is conducted in vivo using mice or rats. READ MORE

  6. 4. Neuroblastoma SH-SY5Y and neural progenitor C17.2 cell lines as models for neurotoxicological studies​

    Author : Jessica Lundqvist; Anna Forsby; Åsa Fex Svenningsen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SH-SY5Y; C17.2; in vitro neurotoxicity; cell culture conditions; biomarkers; in vitro developmental neurotoxicity; whole genome microarray; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : We are surrounded by chemicals, thus understanding how exposure to these chemicals affect us during our life is of great social importance. In order to predict human acute toxicity of chemicals, cosmetics or drugs, development of novel in vitro test strategies is required. READ MORE

  7. 5. Cold-induced nonshivering thermogenesis : tissue origin, activation, recruitment

    Author : Valeria Golozoubova; Martin Brand; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; zoofysiologi; Zoological physiology;

    Abstract : Two types of heat production, shivering and nonshivering thermogenesis, are activated in mammals in the cold. In small mammals, nonshivering thermogenesis becomes the main source of heat upon long-term cold exposure. READ MORE