Search for dissertations about: "adas-cog"

Found 3 swedish dissertations containing the word adas-cog.

  2. 1. Omega-3 fatty acid treatment in mild to moderate Alzheimer's disease : results from the OmegAD study

    Author : Yvonne Freund-Levi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer s disease; progressive neurodegenerative disease; omega-3 fatty acid n-3 FA docosahexaenoic acid; DHA; eicosapentatenoic acid; EPA; linoleic acid; LA; acetylcholinesterase inhibitors; AChEI; Minimental State Examination; MMSE; ADAS-cog; Clinical Dementia Rating scale; CDR; Neuropsychiatric Inventory; NPI; Montgomery Åsberg Depression Rating scale; MADRS; Disability Assessment for Dementia; DAD; Care givers burden CGB; APOEε4; hs-CRP; IL-6; TNF-α and sIL-RII; Aβ42; T-tau and P-tau; weight; Body Mass Index; BMI.;

    Abstract : Alzheimer's disease (AD) is a major public health concern in all countries with an increasing prevalence. It is expected to quadruple by the year 2047. READ MORE

  4. 2. Novel Pharmacometric Methods for Design and Analysis of Disease Progression Studies

    Author : Sebastian Ueckert; Andrew C. Hooker; Mats O. Karlsson; Kayode Ogungbenro; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; optimal design; non-linear mixed effects models; degenerative diseases; Alzheimer s disease; item response theory; statistical power; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : With societies aging all around the world, the global burden of degenerative diseases is expected to increase exponentially. From the perspective drug development, degenerative diseases represent an especially challenging class. READ MORE

  5. 3. Neurodegenerative Biomarkers in Healthy Elderly - with special reference to the preclinical pattern of biological and cognitive markers for Alzheimer’s disease

    Author : Erik Stomrud; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral blood flow; EEG; phosphorylated tau protein; amyloid beta protein; tau protein; cerebrospinal fluid; biomarkers; preclinical Alzheimer s disease; Alzheimer s disease; MCI; dementia; SPECT; memory; cognition; early diagnosis; control groups;

    Abstract : Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. READ MORE