Search for dissertations about: "adenoassociated virus"

Found 2 swedish dissertations containing the words adenoassociated virus.

2. 1. Analysis of HIF-1alpha degradation and function

   Author : Helder André; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Hypoxia-inducible factor-1alpha; protein degradation; prolyl hydroxylases; adenoassociated virus; gene therapy; angiogenesis.;

   Abstract : HIF-1 is a heterodimeric complex of two bHLH/PAS transcription factors, HIF- 1alpha and ANRT. In contrast to the constitutively expressed ARNT, HIF-1alpha protein levels are regulated by oxygen tension. Under normoxic conditions, HIF-1alpha is rapidly degraded by the ubiquitinproteasome pathway. READ MORE

4. 2. Improved human papillomavirus DNA typing methods and biology of cervival cancer

   Author : Biying Zheng; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cervical cancer; human papillomavirus; Pyrosequencing; chemokine receptors; adenoassociated virus; biomarkers; and cell cycle checkpoint.;

   Abstract : Cervical cancer is the second most common cancer among women worldwide. Persistent HPV has been identified as a main risk factor in cervical cancer development. Oncoproteins E6 and E7 of highrisk HPV interact with cellular proteins, subverting cell cycle checkpoint, inducing carcinogenesis. READ MORE