Search for dissertations about: "adenosine diphosphate"

Showing result 1 - 5 of 10 swedish dissertations containing the words adenosine diphosphate.

2. 1. Intracellular mechanisms of skeletal muscle fatigue : role of creatine kinase

   Author : Anders Dahlstedt; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Skeletal muscle fatigue; creatine kinase; inorganic phosphate; adenosine diphosphate;

   Abstract : During intense physical activity the maximal power output of skeletal muscles is reduced, a condition described as muscle fatigue. The cause of impaired muscle function seen in fatigue is multifactorial. READ MORE

4. 2. Platelet activation and aggregation: Clinical and experimental studies

   Author : Sukhi Singh; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Platelet concentrate; Adrenaline; Noradrenaline; Ticagrelor; Platelet aggregation; Platelet activation;

   Abstract : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. READ MORE

5. 3. Novel in vivo therapeutic approaches to Escherichia coli O157:H7 infection

   Author : Ashmita Tontanahal; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; hemolytic uremic syndrome; Shiga toxin; extracellular vesicles; annexin A5; purinergic signaling; ATP; apyrase; IgG; EspP;

   Abstract : Shiga toxin (Stx), the unique virulence factor released by enterohemorrhagic Escherichia coli (EHEC), associated with gastrointestinal infection and in severe cases hemolytic uremic syndrome (HUS). Up until now, no effective therapies have been developed to control disease progression. READ MORE

6. 4. Platelet angiogenic activities and their regulation on endothelial progenitor cell functions

   Author : Zhangsen Huang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Platelets are essential for haemostasis and thrombosis, but also play a major role in angiogenesis. Activated platelets recruit progenitor cells and induce differentiation into endothelial progenitor cells (EPCs), which contribute importantly to vascular regeneration and endothelium reparation. READ MORE

7. 5. Effects of high glucose on platelet activation

   Author : Masoud Razmara; Karolinska Institutet; Karolinska Institutet; Karolinska institutet; []
   Keywords : ;

   Abstract : Diabetes mellitus (DM) is associated with increased cardiovascular mortality and morbidity, due to diabetic angiopathy. Hyperglycaemia is one of the factors that may cause platelet dysfunction in diabetic patients. This work investigated the mechanisms underlying hyperglycaemia-induced platelet hyperreactivity and its impact in diabetic patients. READ MORE