Search for dissertations about: "adenosine kinase"

Showing result 1 - 5 of 41 swedish dissertations containing the words adenosine kinase.

  2. 1. Effects of adenosine and acetylcholine on the lacrimal gland

    Author : Stina K. Carlsson; J. Peter Gierow; Sven Tågerud; Darlene Dartt; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Lacrimal gland; adenosine; adenosine receptors; signal transduction; exocrine secretion; tear film; dry eye; Sjögren’s syndrome; acetylcholine; mitogen activated protein kinase; p38; Cell biology; Cellbiologi; Ophtalmology; Oftalmologi; Cell and molecular biology; Cell- och molekylärbiologi; Cell biology; Cellbiologi; Molecular biology; Molekylärbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : A balanced tear film is essential for a healthy ocular surface. Insufficient tear production may result in dry eye, a common disorder in the elderly population. Dry eye causes significant discomfort in the patients and may lead to visual impairment and ocular infections. READ MORE

  4. 2. Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei

    Author : Munender Vodnala; Anders Hofer; Arne Holmgren; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Trypanosoma brucei; adenosine kinase; thymidine kinase; methylthioadenosine phosphorylase; mouser ribonucleotide reductase; E. coli ribonucleotide reductase; RNR; Ara-A; F-Ara-A; dNTP; NTP; doexynucleotide metabolism; nucleosides; nucleoside kinases; allosteric regulation; biologisk kemi; biological chemistry;

    Abstract : Trypanosoma brucei causes African sleeping sickness in humans and Nagana in cattle. There are no vaccines available against the disease and the current treatment is also not satisfactory because of inefficacy and numerous side effects of the used drugs.T. READ MORE

  5. 3. Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells

    Author : Tova Landström; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3T3-L1 TNF-alpha; adipocyte; insulin; p70S6 kinase; mitogen-activated protein kinase; protein kinase B; phosphatidylinositol-3 kinase; phosphodiesterase 3B; cAMP; lipolysis; phosphorylation; signal transduction; Biochemistry; Metabolism; Biokemi; metabolism;

    Abstract : Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. READ MORE

  6. 4. Interaction between Adenosine and Angiotensin II in Renal Afferent Arterioles of Mice

    Author : Enyin Lai; A. Erik G. Persson; Göran Bergström; Uppsala universitet; []
    Keywords : Physiology; adenosine; angiotensin II; afferent arteriole; calcium; nitric oxide; microperfusion; tubuloglomerular feedback; Fysiologi;

    Abstract : Renal arterioles represent the most important effecter site in the control of renal perfusion and filtration. Adenosine (Ado), angiotensin II (Ang II) and nitric oxide (NO) interact in modulating arteriolar tone. The present work investigates the mechanism of this interaction. READ MORE

  7. 5. Adenosine Regulation of Neutrophil Function

    Author : Stefan Zalavary; Bertil Fredholm; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The neutrophil granulocyte is an essential component of the human immune system. When rrricrobes invade the body, the highly motile neutrophils quickly leave the vascular compartment and approach, engulf and kill the intruders by releasing a battery of antimicrobial substances. READ MORE