Search for dissertations about: "adherens junction"

Showing result 1 - 5 of 11 swedish dissertations containing the words adherens junction.

  2. 1. Regulation of E-cadherin mediated adhesion in thyroid epithelial cells

    Author : Fredrik Larsson; Göteborgs universitet; []
    Keywords : thyroid; adherens junction; E-cadherin; thyrotropin; cAMP; PKA; Epac; IQGAP;

    Abstract : Cell adhesion is one of multicellular organisms most fundamental features. Cells connect to each other by transmembrane proteins arranged in junction complexes. READ MORE

  4. 2. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors

    Author : Yihong Zhu; Göteborgs universitet; []
    Keywords : junction; claudin; ovarian surface epithelium; epithelial ovarian tumor; TGF-?1;

    Abstract : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. READ MORE

  5. 3. The role of angiomotin in endothelial cell motility and cell-cell junction formation

    Author : Anders Bratt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Angiogenesis; cancer; angiostatin; angiomotin; cell motility cell-cell junction; tight junction; adherens junction;

    Abstract : Clinical as well as pre-clinical data show that tumor growth can be restrained by inhibiting angiogenesis. We have been investigating the mechanism of action of angiostatin, an inhibitor of angiogenesis, in order to design novel therapies against cancer. READ MORE

  6. 4. Differential expression pattern of CEACAM1 isoforms in polarized epithelial cells : it's regulation and some functional consequences

    Author : Ulla Sundberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : CEACAM1; adhesion; lateral localization; adherens junctions; desmosomes; primary cilia;

    Abstract : The cell adhesion molecule CEACAM1 is expressed in epithelia, small vessel endothelia and leukocytes as two major, co-expressed isoforms, CEACAM1-L and CEACAM1-S, which differ in their cytoplasmic domains. CEACAM1 has been found both in cell-cell contact areas and on apical surfaces of polarized epithelial cells. READ MORE

  7. 5. The Role of Paladin in Endothelial Cell Signaling and Angiogenesis

    Author : Anja Nitzsche; Mats Hellström; Frank-Dietmar Böhmer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pald1; endothelium; lung; vascular permeability; phosphatase; angiogenesis; Molekylär medicin; Molecular Medicine;

    Abstract : Angiogenesis, the formation of new blood vessels from a pre-existing vasculature, is crucial during development and for many diseases including cancer. Despite tremendous progress in the understanding of the angiogenic process, many aspects are still not fully elucidated. READ MORE