Search for dissertations about: "adiponectin receptors"

Showing result 1 - 5 of 10 swedish dissertations containing the words adiponectin receptors.

  2. 1. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

    Author : Louise Nilsson; Göteborgs universitet; []
    Keywords : prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

    Abstract : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. READ MORE

  4. 2. Membrane Fluidity Regulation: From C. elegans to mammalian cells

    Author : Ranjan Devkota; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PAQR-2; adiponectin receptors; IGLR-2; saturated fats; membrane fluidity; fatty acid desaturation; unsaturated fatty acid; membrane homeostasis;

    Abstract : Biological membranes are primarily an assembly of lipids and proteins. Collectively, these constituents within a phospholipid bilayer determine the physical membrane properties such as fluidity, viscosity, thickness, packing and permeability. Maintenance of membrane properties within acceptable margins, i.e. READ MORE

  5. 3. Pathophysiological regulation of white adipocyte exocytosis of different adiponectin molecular forms

    Author : Musovic Saliha; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; White adipocytes; adiponectin exocytosis secretion; health and metabolic disease;

    Abstract : In this thesis we have identified mechanisms involved in the exocytosis of different adiponectin molecular forms in health and in metabolic disease. We have also studied similarities and differences in depot-specific adipocyte adiponectin release. READ MORE

  6. 4. Ghrelin action on gastrointestinal functions and appetite in rat and man

    Author : Fredrik Levin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ghrelin; ghrelin-receptors; gastrointestinal motility; migrating myoelectric complex; gastric acid secretion; gastric emptying; appetite; food intake; disinhibition; restraint; hunger; obesity;

    Abstract : To study the effect of ghrelin on the contractility of smooth muscle strips in vitro as well as the effects on fasting small bowel motility and acid secretion in vivo in rats and gastric emptying in rats and humans. To study the effect of peripherally administered ghrelin on plasma levels of glucose, insulin, glucagon, orexin A (OXA), somatostatin and gastrin in rats and ghrelin, cholecystokinin (CCK), glucagonlike peptide-1 (GLP-1), peptide YY (PYY) and motilin in humans. READ MORE

  7. 5. On endothelial function in type 2 diabetic patients with coronary artery disease

    Author : Thomas Nyström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Type 2 diabetes; endothelial dysfunction; insulin resistance; coronary artery disease; nitric oxide; glucagon-like peptide 1; exendin; tetrahydrobiopterin; inflammation; adiponectin; resistin; C-reactive protein; tumor necrosis factor a; interleukin-6;

    Abstract : Patients with type 2 diabetes have a poor outcome suffering a myocardial infarction (MI). Endothelial dysfunction may play a role in this poor prognosis. In type 2 diabetes, endothelial dysfunction is a salient feature coexisting with obesity and insulin resistance and may be linked by the same pathophysiology, i.e. READ MORE