Search for dissertations about: "adjuvant chemotherapy"

Showing result 1 - 5 of 91 swedish dissertations containing the words adjuvant chemotherapy.

2. 1. Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker

   Author : Elinor Bexe-Lindskog; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; thymidine phosphorylase; chemotherapy; adjuvant; biological markers; prognosis; practice guidelines; radiotherapy;

   Abstract : Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the gene expression of the enzyme thymidine phosphorylase (TP), which was related to prognostic factors (paper I, n=254), evaluated as a predictive factor (paper III, n=125), and assessed by change of treatment (paper II, n=28). READ MORE

4. 2. Neurotoxic side effects and impact on daily life in patients with colorectal cancer with adjuvant oxaliplatin-based chemotherapy

   Author : Jenny Drott; Carina Berterö; Hans Starkhammar; Karin Kjellgren; Sussanne Börjeson; Yvonne Wengström; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer care; Cancer nursing; Colorectal cancer; Neurotoxicity; Neuropathy; Oxaliplatin; Chemotherapy; Patient-reported outcomes; Health; Qualitative study; Longitudinal study; mHealth;

   Abstract : Introduction: Colorectal cancer (CRC) is one of the most common cancers globally. Chemotherapeutic drugs are frequently used in postoperative treatment. The platinum compound oxaliplatin (OXA) is an option for adjuvant treatment of patients with resected CRC, and has been shown to improve survival. OXA-induced neurotoxic side effects are common (e. READ MORE

5. 3. Resection of colorectal liver metastases - Impact of preoperative chemotherapy

   Author : Sam Eriksson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal liver metastases; Preoperative chemotherapy; Liver resection; Hepatic microcirculation; Sarcopenia;

   Abstract : Background Colorectal cancer is a leading cause of cancer related death worldwide. 20-30 % of patients will develop colorectal liver metastases (CRLMs). Surgical resection is the mainstay of treatment for CRLMs, and is often combined with perioperative chemotherapy, which can prolong progression-free survival after resection. READ MORE

6. 4. Chemosensitivity in Breast Cancer

   Author : Kenneth Villman; Carl Blomqvist; Ulf Tidefelt; Nils Wilking; Uppsala universitet; []
   Keywords : Oncology; breast cancer; chemotherapy; anthracycline; predictive; topoisomerase; TOP2A; HER2; cyclin A; in vitro; Onkologi;

   Abstract : Breast cancer mortality in Sweden is now in decline, thanks to early detection and the wide use of adjuvant endocrine therapy and chemotherapy. While hormone receptor status is predictive of response to endocrine treatment, there is no clinically useful predictive marker of a patient’s response to chemotherapy. READ MORE

7. 5. Folates in the treatment of colorectal cancer

   Author : Helena Taflin; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Folate; Colorectal cancer; leucovorin; modufolin; LC-MS MS; polymorphisms; MTHFR; adjuvant chemotherapy;

   Abstract : ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most common cancers in the world, and radical surgery with total removal of the tumour (RO-resection) is the single most important treatment. However, chemotherapy is recommended for patients with risk factors and patients with metastatic disease. READ MORE