Search for dissertations about: "adjuvants"

Showing result 16 - 20 of 69 swedish dissertations containing the word adjuvants.

2. 16. Enhancement of HIV-1 DNA immunogens

   Author : Anne Kjerrström Zuber; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HIV-1; DNA vaccination; regulatory genes; adjuvants; experimental HIV-1 model;

   Abstract : Human immunodeficiency virus type 1 eludes control by the immune response through a high degree of variability and immune escape mechanisms. Induction of a broad specific immune response is important to clear virus-infected cells. READ MORE

4. 17. Novel allergen preparations for use in allergen-specific immunotherapy

   Author : Theresa Neimert Andersson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Allergy; allergen-specific immunotherapy; adjuvants; carbohydrate-based particles; allergic asthma; mouse models; hypoallergens;

   Abstract : Allergy is a common disease in the industrialized countries, affecting approximately 25% of the population. Therefore, there is a need to find new treatment strategies to improve the quality of life for allergic individuals. Today the only treatment that gives long-lasting reduction of allergic symptoms is allergen-specific immunotherapy (SIT). READ MORE

5. 18. Studies of the immunopathogenesis in three arthritis models in rats

   Author : Helena Erlandsson Harris; Karolinska Institutet; Karolinska Institutet; []
   Keywords : experimental arthritis; inflammation; adjuvants; T-cell receptor; collagen type II; cartilage oligomeric matrix protein COMP ;

   Abstract : The immunopathogenesis of three arthritis models has been studied; oil-induced arthritis (OIA), homologous collagen-induced arthritis (CIA) and COMP-induced arthritis. The induction of a monophasic arthritis, OIA, in the DA rat with a single intradermal injection of Freund's incomplete adjuvant (FIA) was reported. READ MORE

6. 19. Enhancing T cell mediated immunity in DNA vaccination

   Author : Jan Alvar Lindencrona; Karolinska Institutet; Karolinska Institutet; []
   Keywords : DNA vaccination; CTL; T cell; IFN-gamma; anti-tumor immunity; HER-2 neu; Influenza; LCMV; Virus-Like Particles; murine models; adjuvants; immunotherapy;

   Abstract : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. READ MORE

7. 20. Patch testing with palladium and aluminium, epidemiological and experimental studies

   Author : Lisbeth Rosholm Comstedt; Yrkes- och miljödermatologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Contact allergy to palladium; prevalence of metal allergy; patch testing with palladium; natrium tetrachloropalladate; palladium chloride; Finn Chamber; patch testing with aluminium; isolated palladium allergy; patch test system; adjuvants in patch testing; delayed hypersensitivty reaction;

   Abstract : AbstractThe aim of this thesis was to investigate the prevalence and significance of contact allergy to palladium from a Swedish perspective. Our initial findings made it necessary to also explore the importance of the metal aluminium used in test chamber systems and the effect of aluminium chloride (Al-Cl) in patch test preparations. READ MORE