Search for dissertations about: "adoptive transfer"
Showing result 1 - 5 of 46 swedish dissertations containing the words adoptive transfer.
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1. Immunomodulatory properties of steroid hormones
Abstract : Recent epidemiological, clinical and experimental evidence have suggested that steroid hormones play an important role in immune responses and in immune-mediated diseases. Many autoimmune diseases are treated with corticosteroids. READ MORE
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2. Adoptive T Cell Therapy for Treatment of Metastatic Melanoma
Abstract : Malignant melanoma is a common type of solid tumor that causes high cancer-related mortality in young adults of Northern Europe. The incidence of melanoma increases rapidly which renders us a special responsibility to investigate this disease in depth. READ MORE
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3. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells
Abstract : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. READ MORE
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4. Improvement of adoptive T-cell therapy for Cancer
Abstract : Cancer immunotherapy has recently made remarkable clinical progress. Adoptive transfer of T-cells engineered with a chimeric antigen receptor (CAR) against CD19 has been successful in treatment of B-cell leukemia. READ MORE
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5. Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity
Abstract : Allogeneic stem cell transplantation (SCT) can cure leukaemia, aplastic anaemia, and some inborn errors of metabolism and immunodeficiencies in children. As only 113 of patients who need SCT have an HLA-identical sibling, the use of alternative donors has increased, to over 50% of all paediatric SCTs at our centre. READ MORE