Search for dissertations about: "adrenal hyperplasia"
Showing result 1 - 5 of 29 swedish dissertations containing the words adrenal hyperplasia.
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1. Congenital adrenal hyperplasia in adults
Abstract : Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. More than 95% of CAH cases are caused by reduced 21-hydroxylase function leading to variable extent of cortisol and aldosterone deficiency in addition to androgen excess. The foundation of CAH treatment is the use of glucocorticoids. READ MORE
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2. Molecular analysis of mutated P450c21 in congenital adrenal hyperplasia
Abstract : Defects in cytochrome P450c21 (21-hydroxylase, 210H) are the most common causes of congenital adrenal hyperplasia (CAH). This recessively inherited disorder demonstrates a wide spectrum of severity as a consequence of impaired production of cortisol and aldosterone and excessive secretion of adrenal androgens. READ MORE
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3. Congenital adrenal hyperplasia, CYP21 deficiency, screening and clinical aspects
Abstract : Congenital adrenal hyperplasia (CAH) is a group of recessively inherited disorders. More than 90% of all cases of CAB are caused by 21-hydroxylase deficiency. This enzyme deficiency results in reduced ability to synthesize cortisol and aldosterone and at the same time increased secretion of androgens. READ MORE
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4. Functional and structural studies on CYP21 mutants in congenital adrenal hyperplasia
Abstract : Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is one of the most common autosomal recessive disorders, affecting around 1/10 000 newborns worldwide. A defect in the gene encoding steroid 21-hydroxylase, CYP21, results in impaired synthesis of cortisol and in most cases also aldosterone. READ MORE
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5. Polycystic ovary syndrome - morphologic and dynamic evaluation by magnetic resonance imaging
Abstract : Polycystic ovary syndrome (PCOS) is a complex endocrine disorder, affecting up to 15% of women of reproductive age. The syndrome is characterized by oligo-anovulation, hyperandrogenism and polycystic ovaries. What constitutes the best definition of PCOS is still a matter of debate. READ MORE