Search for dissertations about: "adrenoceptor blockade"

Showing result 1 - 5 of 10 swedish dissertations containing the words adrenoceptor blockade.

  1. 1. Mental Stress and Endothelium-Dependent Vasodilation

    Author : Kristina Johansson; Sverker Jern; Uppsala universitet; []
    Keywords : Medical sciences; Mental stress; endothelium; adrenoceptor blockade; catecholamine; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : The endothelium plays an important part in blood flow regulation by producing the vasodilatory substance nitric oxide (NO). Various studies have shown that commonly accepted risk factors for coronary heart disease, such as hypertension, diabetes, hypercholesterolemia, smoking and mental stress impair endothelium-derived vasodilation by the NO-pathway. READ MORE

  2. 2. Bronchial hyperresponsiveness of ß-adrenoceptor agonists and antagonists in guinea pig airways

    Author : Fredrik Johansson; Sven-Erik Dahlén; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Asthma is one of the most common diseases in the industrialised countries. The underlying mechanisms are complex and still not fully understood although inflammation of the airways plays an important role. READ MORE

  3. 3. Mechanism of action of antipsychotic drugs : focus on the nucleus accumbens and the prefronta cortex : an experimental study

    Author : Monica M Marcus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Schizophrenia; antipsychotic drug; nucleus accumbens shell; nucleus accumbens core; prefrontal cortex; dopamine; 5-11T2A receptor; alpha1 adrenoceptor; C12 adrenoceptor; glutamate; nicotine.;

    Abstract : Antipsychotic drugs have been classified as typical or atypical. To achieve an effective antipsychotic effect with typical antipsychotic drugs, e.g. haloperidol, a dopamine D2 receptor blockade of about 70% seems necessary. READ MORE

  4. 4. Cardiovascular and sympatho-adrenal responses to mental stress with special reference to the regulation of human forearm blood flow

    Author : Madeleine Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adrenaline; axillary blockade; beta-receptor blockader; calcium channel blockers; cholinergic blockingagents; felodipine; hypertension-primary; noradrenaline; skeletal muscle; sodium nitroprusside; stress-psychologicai; vascular resistance;

    Abstract : The cardiovascular and sympatho-adrenal responses to a standardized mental stress test (Stroop's colour word conflict test CWT) were studied in 63 healthy and 11 hypertensive men by intraarterial pressure measurements, forearm blood flow by occlusion plethysmography and noradrenaline (NA) and adrenaline (ADR) determinations in arterial and venous plasma. One study included central hemodynamics by right heart catheterization and NA turnover by an isotope dilution method, permitting studies of NA kinetics in the whole body and in a regional vascular bed (the forearm) in hypertensive patients and age-matched controls. READ MORE

  5. 5. Sensory neuropeptides and nitric oxide in nasal vascular regulation

    Author : Johan Rinder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sensory nerves; neuropeptides; nasal mucosa; nitric oxide; vascular regulation; acoustic rhinometry; NK1-receptors; CGRP-receptors; vanilloid receptors; capsaicin; lactic acid; exercise; a-adrenoceptor agonists; pig; human.;

    Abstract : The role of sensory neuropeptides and nitric oxide in vascular regulation was investigated in the pig nasal mucosa in vivo using arterial blood flow measurements and acoustic rhinometry for analysis of capacitance function. Moreover, the effects of heavy physical exercise, a-adrenoceptor agonists, nitric oxide synthase (NOS) inhibition, L-arginine, nitric oxide (NO) gas, histamine and capsaicin on nasal cavity NO levels and nasal cavity volume, were investigated in healthy subjects. READ MORE