Search for dissertations about: "adult acute lymphoblastic leukemia"

Showing result 1 - 5 of 11 swedish dissertations containing the words adult acute lymphoblastic leukemia.

2. 1. Population-based studies on acute leukemias - lessons from the Swedish Adult Acute Leukemia Registry

   Author : Lovisa Vennström; Göteborgs universitet; []
   Keywords : Acute leukemia; population-based; incidence; survival; acute myeloid leukemia; acute lymphoblastic leukemia; acute promyelocytic leukemia; early death;

   Abstract : Acute leukemia (AL) is a rare, potentially curable, aggressive neoplasm of hematopoietic origin. AL is a heterogeneous disease and is further subdivided according to clinical and biological features. READ MORE

4. 2. Prognostic factors, treatment and outcome in adult acute lymphoblastic leukemia : Population-based studies in Sweden

   Author : Piotr Kozlowski; Helene Hallböök; Maria Åström; Anita W. Rijneveld; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute Lymphoblastic Leukemia; adult; chemotherapy; prognosis; population-based; Onkologi; Oncology;

   Abstract : Acute lymphoblastic leukemia (ALL) has poor prognosis in older/elderly adults and in high-risk/relapsed disease. Recommended treatment of ALL was evaluated (study I-IV). Data was obtained from the Swedish Acute Leukemia registries and from patient records.I. READ MORE

5. 3. Molecular Genetic Characterization of Acute Lymphoblastic Leukemia with a Poor Prognosis

   Author : Setareh Safavi; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute lymphoblastic leukemia; hypodiploidy; adult acute lymphoblastic leukemia;

   Abstract : Acute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children 50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. READ MORE

6. 4. Registry-Based Studies in Adult Acute Lymphoblastic Leukemia in Sweden : Survival and Quality of Life

   Author : Emma Bergfelt Lennmyr; Helene Hallböök; Martin Höglund; Jan Maxwell Nørgaard; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute Lymphoblastic Leukemia; Philadelphia Chromosome; Overall Survival; Population-based; Quality Registry; Relapse; Patient-Reported Outcome; Health-Related Quality of Life; Depression;

   Abstract : Acute lymphoblastic leukemia (ALL), a common child malignancy, also constitutes a minor fraction of adult cancer with approximately 50 new cases per year in Sweden. While the five-year overall survival (OS) in pediatric ALL is more than 90%, the prognosis in adults is dismal. READ MORE

7. 5. Significance of Wilms’ tumor gene 1 as a biomarker in acute leukemia and solid tumors

   Author : Charlotta Andersson; Eva Lundin; Aihong Li; Andreas Jonsson; Xingru Li; David M. Loeb; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wilms’ tumor gene 1; biomarker; leukemia; renal cell carcinoma; ovarian carcinoma; Clinical Chemistry; klinisk kemi; patologi; Pathology;

   Abstract : Wilms’ tumor gene 1 (WT1) is a zinc finger transcriptional regulator with crucial functions in embryonic development. Originally WT1 was described as a tumor suppressor gene, but later studies have shown oncogenic properties of WT1 in a variety of tumors. Because of its dual functions in tumorigenesis, WT1 has been described as a chameleon gene. READ MORE