Search for dissertations about: "adult onset GHD"

Found 5 swedish dissertations containing the words adult onset GHD.

2. 1. Long-term effects of growth hormone replacement therapy in growth hormone deficient adults

   Author : Galina Götherström; Göteborgs universitet; []
   Keywords : growth hormone; body composition; bone mass; bone density; muscle strength; lipids; glucose metabolism; adult onset GHD; childhood onset GHD; gender;

   Abstract : Deficiency of growth hormone (GHD) in adults results in abnormal body composition, reduced bone mass and muscle strength, deteriorated cardiovascular risk factors. Short-term GH replacement reverses many of the symptoms associated with adult GHD. READ MORE

4. 2. Aspects of diagnosis and treatment of hypopituitarism in adult life

   Author : Helena Filipsson; Göteborgs universitet; []
   Keywords : hypopituitarism; pituitary; diagnosis; treatment; GHD; central hypothyroidism; genetic; idiopathic; ACTH insufficiency; discontinuation;

   Abstract : Management of adult patients with hypopituitarism can improve with better char¬ac¬terisation of idiopathic pituitary insufficiency (IPI) and clearer diagnosis of central hy¬pothy¬roidism (CH). Moreover, optimised treatment strategies for glucocorticoid (GC) re¬placement therapy and of long-term growth hormone (GH) in GH deficiency (GHD) are needed. READ MORE

5. 3. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment

   Author : Elena Lundberg; Berit Kriström; Kerstin Albertsson-Wikland; Roland Pfäffle; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gain in height; puberty; IGHD; non-GHD; IGF-I; bioavailability;

   Abstract : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. READ MORE

6. 4. Bone health and cardiovascular risk in hypopituitary patients on complete hormone replacement, including GH

   Author : Helene Holmer; Lund Medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; diabetologi; Endokrinologi; Craniopharyngioma; insulin tolerance test; Endocrinology; secreting systems; diabetology; cardiovascular risk; growth hormone deficiency; fracture incidence; bone mineral density; growth hormone replacement;

   Abstract : Growth hormone deficiency (GHD) is associated with decreased bone mineral density (BMD). Low BMD is correlated to increased fracture risk. There are no studies on fracture risk in GHD patients on GH therapy and no studies on BMD in adults with childhood onset (CO) craniopharyngioma (CP) on GH therapy. READ MORE

7. 5. Long-term effects of growth hormone replacement in hypopituitary adults on body composition, bone mass and cardiovascular risk factors

   Author : Mariam Elbornsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone; growth hormone deficiency; growth hormone replacement; bone mineral density; body composition; muscle strength; elderly; cardiovascular risk factors; pituitary irradiation;

   Abstract : Growth hormone (GH) deficient (GHD) adults have decreased bone mass and muscle strength, impaired body composition, disturbed serum lipid pattern and increased morbidity and mortality in cardiovascular and cerebrovascular diseases. GH replacement normalizes most of these aberrations within the first year of treatment. READ MORE