Search for dissertations about: "adult-onset"
Showing result 1 - 5 of 36 swedish dissertations containing the word adult-onset.
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1. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes
Abstract : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. READ MORE
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2. The female offender : patterning of antisocial and criminal behaviour over the life-course
Abstract : The studies included in the thesis illustrate the patterning of female offending over the life course. The overarching aim is to contribute to a better understanding of the female offender and of the heterogeneity in female criminal offending trajectories over the life course, and also of factors that differentiate between these trajectories. READ MORE
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3. Radiological studies of LMNB1-related autosomal dominant leukodystrophy and Marinesco-Sjögren syndrome
Abstract : There are approximately 6000 to 8000 rare diseases, each with a prevalence of less than 1 / 10 000, but in aggregate affecting 6 to 8% of the population. It is important to evaluate disease development and progression to know the natural course of any disease. READ MORE
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4. Immunoregulatory differences between adult onset type 1 diabetes and latent autoimmune diabetes in adults (LADA)
Abstract : Autoimmune diabetes is characterized by cell mediated autoimmunity against insulin producing beta cells in pancreatic islets. Type 1 diabetes is the major cause of diabetes in children and adolescents and is believed to be mediated by a Thl driven destruction of beta cells. READ MORE
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5. Long-term effects of growth hormone replacement therapy in growth hormone deficient adults
Abstract : Deficiency of growth hormone (GHD) in adults results in abnormal body composition, reduced bone mass and muscle strength, deteriorated cardiovascular risk factors. Short-term GH replacement reverses many of the symptoms associated with adult GHD. READ MORE