Search for dissertations about: "adult-onset"

Showing result 21 - 25 of 30 swedish dissertations containing the word adult-onset.

  1. 21. Metabolomics studies of ALS a multivariate search for clues about a devastating disease

    University dissertation from Umeå : Umeå university

    Author : Anna Wuolikainen; Umeå universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyotrophic lateral sclerosis ALS ; motor neuron disease; Lou Gehrig’s disease; human disease; CSF; biomarkers; metabolomics; metabonomics; chemometrics; design of experiments; multivariate analysis.; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Neurology; neurologi;

    Abstract : Amyotrophic lateral sclerosis (ALS), also known as Charcot’s disease, motor neuron disease (MND) and Lou Gehrig’s disease, is a deadly, adult-onset neurodegenerative disorder characterized by progressive loss of upper and lower motor neurons, resulting in evolving paresis of the linked muscles. ALS is defined by classical features of the disease, but may present as a wide spectrum of phenotypes. READ MORE

  2. 22. Epidemiological studies of childhood diabetes and important health complications to the disease

    University dissertation from Umeå : Umeå universitet

    Author : Yonas Berhan; Umeå universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type- 1 diabetes; type-2 diabetes; end stage renal disease; mortality; socioeconomic status; Epidemiology; epidemiologi;

    Abstract : Background and aims: The overall aim of this thesis was to increase knowledge regarding the occurrence of childhood onset T1D and T2D in Sweden and in relation to that describe and elucidate important aspects on two grave complications to diabetes; end-stage renal disease (ESRD) and mortality. The two first studies included in this thesis aimed to describe and analyze the cumulative incidence of childhood onset T1D in Sweden and to assess the occurrence of undetected T2D in Swedish children. READ MORE

  3. 23. Hearing-related symptoms among women - Occurrence and risk in relation to occupational noise and stressful working conditions

    University dissertation from Umeå : Umeå universitet

    Author : Sofie Fredriksson; Göteborgs universitet.; Gothenburg University.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hearing Disorders; Noise; Occupational; Occupational Stress; Women; Working;

    Abstract : A considerable amount of research has been devoted to the risk of noise-induced hearing loss among industry workers – the majority of whom are men. Much less research has been done in female-dominated human service occupations, including obstetrical care and preschools. READ MORE

  4. 24. Immunogenetic studies in autoimmune endocrine diseases

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Giovanni Gambelunghe; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type I Diabetes; LADA; Addison s disease; HLA; MICA; MICB; autoantibodies;

    Abstract : Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterised by Tlymphocyte infiltration of islets of Langerhans with consequent destruction of beta cells. A permissive genetic background is required for the development of the islet autoimmune process. READ MORE

  5. 25. SOD, ORF and ALS: On the role of SOD1 and C9ORF72 in the pathogenesis of ALS

    University dissertation from Umeå : Umeå University

    Author : Isil Keskin; Umeå universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; Misfolded species;

    Abstract : Amyotrophic lateral sclerosis (ALS) is characterized by adult-onset degeneration of upper and lower motor neurons. Symptoms begin focally in one muscle and then spread contiguously, resulting in progressive paralysis and death from respiratory failure. READ MORE