Search for dissertations about: "advanced glycation end products"

Showing result 16 - 20 of 21 swedish dissertations containing the words advanced glycation end products.

  2. 16. Synaptic elimination and the complement system in Alzhaimer's disease

    Author : Jonny Daborg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synapse; Alzheimer s disease; Genetics; CSF; Complement; RAGE;

    Abstract : The mechanisms behind Alzheimer’s disease (AD) are largely unknown. The disease is to a large extent hereditary, and the best pathophysiological correlate to the severity of the symptoms is loss of synapses. READ MORE

  4. 17. Cardiovascular morbidity and metabolic signature in patients with rheumatoid arthritis

    Author : Mitra Nadali; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular mortality; Rheumatoid arthritis; metabolic signature;

    Abstract : Background and objectives: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease with excess risk for cardiovascular morbidity and mortality. The treatment of RA by anti-inflammatory drugs has dramatically been improved over the resent decades. READ MORE

  5. 18. Studies of high mobility group chromosomal protein 1 as a pro-inflammatory cytokine

    Author : Gail E Mullins; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HMGB1; endothelial cells; pro-inflammatory; cytokine; RAGE;

    Abstract : High mobility group box chromosomal protein 1 (HMGB 1) is a nuclear protein recently recognised as a pro-inflammatory cytokine with implications both in acute and in chronic inflammation. HMGB1 has been reported to act as a late mediator of septic shock in mice. READ MORE

  6. 19. On cardiovascular complications in people with type 2 diabetes : Aspects of incretin-based therapy and glycemic control

    Author : Irene Santos Pardo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Hyperglycemia, insulin resistance, and the presence of advanced glycation end products are key features of type 2 diabetes (T2DM) and the leading mechanisms behind the increased cardiovascular risk observed in people with this condition. Percutaneous coronary revascularization has been associated with higher risk of stent failure in people with diabetes mellitus (DM), having greater risk of both in-stent restenosis (ISR) and stent thrombosis (ST). READ MORE

  7. 20. Early life influences on adult organ function, health and disease, including data from Swedish population-based cohorts

    Author : Shantanu Sharma; Internmedicin - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EPIDEMIOLOGY; Preconception care; Cardiovascular biomarkers; birth weight; gestational age; neoplasms; lipoprotein; prenatal care; pulse wave analysis;

    Abstract : Prenatal insults or adverse events during the in-utero period may lead to suboptimal function of adult organs because of the impairment of critical organ development and growth, as linked to lower birth weight. This may ultimately predispose the individual to the later onset of some diseases in adulthood, a process known as Developmental Origins of Health and Disease (DOHaD). READ MORE