Search for dissertations about: "adverse effects"
Showing result 11 - 15 of 1026 swedish dissertations containing the words adverse effects.
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11. Cardiovascular effects of diesel exhaust : mechanistic and interventional studies
Abstract : Background: Air pollution is associated with negative health effects. Exposure to combustion-derived particulate matter (PM) air pollution has been related to increased incidence of cardiovascular and respiratory morbidity and mortality, specifically in susceptible populations. Ambient particles, with a diameter of less than 2. READ MORE
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12. Medication adherence, side effects and patient-physician interaction in hypertension
Abstract : Hypertension is an important risk factor for cardiovascular disease, the incidence of which it is possible to reduce by prophylactic treatment with antihypertensive drugs. In clinical practice, however, only a minority of patients reach target blood pressure levels. READ MORE
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13. Congestion Charging in Urban Networks : Modelling Issues and Simulated Effects
Abstract : One of the major challenges cities face today, in their development towards sustainable urban areas, is the need for an efficient and environmentally friendly transport system. This transport system should manage to tie together the city without strong adverse impact on urban environment, air-quality and climate change. READ MORE
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14. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?
Abstract : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. READ MORE
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15. Pharmacogenetics and Antipsychotic Treatment in Schizophrenia with Special Focus on Adverse Drug Reactions
Abstract : Genetically determined differences in drug metabolism and disposition and drug targets play a pivotal role in the interindividual variability in the clinical outcome of antipsychotic treatment. The aim of this thesis was to study the impact of polymorphisms in genes involved in the pharmacokinetics and pharmacodynamics of antipsychotics, with special focus on their extrapyramidal and metabolic adverse effects. READ MORE