Search for dissertations about: "adverse events"

Showing result 11 - 15 of 420 swedish dissertations containing the words adverse events.

  1. 11. Checkpoint inhibitor-induced adverse events in the CNS - T-cell characteristics and biomarkers

    Author : Sara Bjursten; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; Immune checkpoint inhibition; Immune related adverse events to the CNS; T cells;

    Abstract : Immune checkpoint inhibitors (ICI) activate T cells to kill cancer cells by blocking inhibitory receptors PD-1 (nivolumab; nivo) or CTLA-4 (ipilimumab; ipi). Activated T cells can also attack any healthy organ, causing unpredictable immune related adverse events (irAE). The risk of irAE is highest when treating with ipi and nivo simultaneously. READ MORE

  2. 12. LIFE EVENTS, STRESS AND COPING

    Author : Charlotta Sunnqvist; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coping strategies; biological stressmarkers; SUAS-S; Suicide attempt; time-geographic life charting;

    Abstract : In order to increase the understanding of suicidal behaviour, the general aim of the thesis is to gain a profound knowledge of the suicidal individual, and hence to find and ensure a preventive strategy. This will be accomplished by finding and trying new methods for evaluation of suicide risk. READ MORE

  3. 13. Clinical studies of thiopurine metabolism in inflammatory bowel disease

    Author : Ulf Hindorf; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterologi; Gastro-enterology; thiopurine methyltransferase; 6-mercaptopurine; azathioprine; Inflammatory bowel disease; thiopurines; adverse events; methylated metabolites; thioguanine nucleotides;

    Abstract : Inflammatory bowel disease (IBD, i.e. primarily Crohn's disease and ulcerative colitis) is characterised by a chronic or relapsing inflammation of the digestive tract. READ MORE

  4. 14. Clinical results after hip fracture - with special focus on hip arthroplasty

    Author : Susanne Hansson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : hip fracture; femoral neck fracture; arthroplasty; complications; adverse events; patient-reported outcome measures PROM; rehabilitation;

    Abstract : Hip fractures are of major concern worldwide, but even if literature isabundant, there are still gaps to fill. The global outcome needs to be betterunderstood, including patient-reported outcome. Many studies focus onimproving surgical outcome, with less focus on medical complications. READ MORE

  5. 15. Population-based studies of higher-level gait disorders and hydrocephalus : focused on brain ventricular morphometry and patient outcomes following shunt surgery

    Author : Jenny Larsson; Jan Malm; Anders Eklund; Hanna Israelsson Larsen; Lars-Owe D. Koskinen; Uwe Kehler; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Higher-level gait disorder; Idiopathic Normal Pressure Hydrocephalus; Ventriculomegaly; Falls; Fear of Falling; Self-efficacy; Depression; Quality of life; Adverse events; Headache; Epilepsy; Abdominal pain;

    Abstract : Background: To study gait is of great importance for the health of the aging population. Higher-level gait disorders (HLGD) are characterized by a slow, symmetrical, unsteady gait. Its cause is most often unknown. HLGD in combination with ventriculomegaly (i. READ MORE