Search for dissertations about: "affinity ligand"
Showing result 16 - 20 of 231 swedish dissertations containing the words affinity ligand.
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16. Antibody-Fragments: Protein Engineering, Process Development, and their Application as Affinity Ligands
Abstract : Monoclonal antibody (mAb) fragments have become the formats of choice for both biopharmaceuticals and ligands in analytical and preparative applications. Their smaller size enables additional advantages over full-length mAbs, such as improved tissue penetration, faster blood clearance for diagnostic applications, improved capacity, and enablement of multivalent formatting. READ MORE
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17. Fluorescence-based ligand assays for protein detection using affibody affinity proteins
Abstract : The detection and quantification of biomolecules, and proteins in particular, are of great interest since these molecules are of fundamental importance to our well-being. Body fluids, as for instance human blood, are well suited for sampling of protein levels. READ MORE
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18. Affinity Two-Phase Partitioning of Liposomes and Membranes
Abstract : Affinity two-phase partitioning based on an immunoaffinity sandwich approach for the rapid and selective purification of membranes is presented in this thesis. The method was developed by studying different parameters governing the affinity partitioning of model membranes. To this end, biotinylated liposomes were used. READ MORE
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19. Modeling Kinetics of Protein-Ligand Systems
Abstract : Protein-ligand interactions dominate many life activities and are crucial for thedevelopment of tracers for diagnosing diseases and drugs for treating diseases.For protein-ligand interactions, the binding affinity is conventionally believedto be the most important indicator. READ MORE
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20. Computational Studies of Protein-ligand Systems Using Enhanced Sampling Methods
Abstract : This thesis focuses on studies of protein-ligand systems using enhanced sampling methods. In chapter I, I give a brief introduction to the time-scale problem and some enhanced sampling methods. In chapter II, the basics of MD simulation are reviewed. READ MORE