Search for dissertations about: "age eGFR"

Showing result 1 - 5 of 30 swedish dissertations containing the words age eGFR.

  2. 1. Studies on the Roles of PDGFRA and EGFR in the Classification and Identification of Therapeutic Targets for Human Gliomas

    Author : Dongfeng Chen; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gliomas; classification; EGFR; PDGFRA; FGF2; surface expression; cell proliferation;

    Abstract : Glioma is the most common type of primary tumor in the adult central nervous system (CNS). However, the current classification of gliomas is highly subjective and even inaccurate in some cases, which leads to clinical confusion and hinders the development of targeted therapies. READ MORE

  4. 2. Risk and prognostic factors for malignant glioma

    Author : Sara Sjöström; Beatrice S Melin; Ulrika Andersson; Monika Hegi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; Glioblastoma; Risk; Outcome; EGR; EGFR; VEGF; VEGFR; DNA repair; virus; Oncology; Onkologi; onkologi; Oncology;

    Abstract : Background: Glioblastoma is the most common and aggressive type of glioma and associated with poor prognosis. Apart from ionizing radiation and some rare genetic disorders, few aetiological factors have been identified for primary brain tumours. READ MORE

  5. 3. Prognostic Factors in Early Stages (FIGO I-II) of Epithelial Ovarian Carcinoma

    Author : Ingirídur Skírnisdóttir; Seija Grenman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Ovarian cancer; early stages; adjuvant therapy; prognosis; tumor grade; apoptotic regulators; p53; bcl-2; bax; growth factor receptors; HER-2 neu; EGFR; DNA ploidy; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

    Abstract : From January, 1988, to December, 1993, 113 patients with FIGO stage IA-IIC epithelial ovarian carcinoma were treated with postoperative radiotherapy. The median follow-up period was 74 months. Tumor recurrences were recorded in 33 cases (30%). The cancer-specific survival rate was 72%. READ MORE

  6. 4. Genetics of Diabetes Subtypes. Characterization of novel cluster-based diabetes subtypes

    Author : Dina Mansour Aly; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Precision medicine; Diabetes Subclassification; genome-wide association studies; GWAS; genetic risk scores; GRS; chronic kidney disease; CKD; diabetic kidney disease; DKD; Estimated glomerular filtration rate; eGFR; ANDIS; diabetes; diabetics;

    Abstract : BACKGROUND: Type 2 diabetes (T2D) has been reproducibly clustered into five subtypes based on six-clinical variables; age at diabetes onset, body mass index (BMI), Glutamic acid decarboxylase autoantibodies (GADA), glycated hemoglobin (HbA1c) and insulin secretion and resistance estimated as HOMA2B and HOMA2IR derived from fasting glucose and Cpeptide. These subtypes have different disease progression and risk of complications. READ MORE

  7. 5. The epidemiology, biology and genetics of human astrocytic tumours

    Author : Magnus Bäcklund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cancer; cell cycle; apoptosis; astrocytic glioma; glioblastoma; Rb 1 pathway; p53 pathway; EGFR; PTEN; prognosis; parathyroid adenoma; epidemiology;

    Abstract : In Sweden > 1000 primary central nervous system (CNS) tumours are diagnosed each year. The majority are malignant and in adults astrocytic gliomas dominate. READ MORE