Search for dissertations about: "age related macular degeneration"

Showing result 11 - 15 of 32 swedish dissertations containing the words age related macular degeneration.

  2. 11. Developmental insights and biomedical potential of human embryonic stem cells : modelling trophoblast differentiation and establishing novel cell therapies for age-related macular degeneration

    Author : Álvaro Plaza Reyes; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Understanding the molecular pathways responsible for lineage segregation in the preimplantation human embryo is critical in order to fully elucidate the mechanisms involved in pluripotency and differentiation of embryonic stem cells. A significant increase in our comprehension of such processes will lead to an improvement in the quality and efficiency of these cells for applications requiring stem cell maintenance and differentiation, such as regenerative medicine. READ MORE

  4. 12. Human embryonic stem cells for retinal repair : preclinical in vitro and in vivo studies for the treatment of age-related macular degeneration with human embryonic stem cell-derived retinal pigment epithelial cells

    Author : Sandra Petrus-Reurer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Age-related macular degeneration (AMD) is the major cause of vision loss in the industrialized countries in people above sixty years of age. The dry advanced form of the disease, also termed as geographic atrophy (GA), is characterized by the progressive death of retinal pigment epithelial cells (RPE) and consequent loss of the adjacent photoreceptor (PR) layer, leading to an impaired visual function. READ MORE

  5. 13. Oxidative stress-related damage of retinal pigment epithelial cells : possible protective properties of autophagocytosed iron-binding proteins

    Author : Markus Karlsson; Christina Frennesson; Sven Erik Nilsson; Tino Kurz; Ulf Brunk; Anders Kvanta; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Oxidative stress is a major pathogenic factor in the development of age-related macular degeneration (AMD), which is the most common cause of severe central visual impairment in the elderly population in the western world.It is believed that the degenerative process starts in the retinal pigment epithelium (RPE). READ MORE

  6. 14. Retinal function in deaf-blind syndromes

    Author : Eva Malm; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; general anesthesia.; molecular genetics; hearing impairment; full-field electroretinography; Retinal degeneration;

    Abstract : A variety of disorders can cause retinal degeneration and hearing impairment, and it is of great value to have an early diagnosis since there is a large variation in phenotype and prognosis both within and between the different disorders. The general aim of this thesis was to characterize the retinal function, to describe the phenotype, and – where appropriate – to relate the phenotype to genotype in patients with combined visual and hearing impairment. READ MORE

  7. 15. Visual, musculoskeletal, and balance symptoms in people with visual impairments

    Author : Christina Zetterlund; Lars-Olov Lundqvist; Hans O. Richter; Tony Pansell; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Visual impairment; musculoskeletal symptoms; balance symptoms; visual enhancing aids; age-matched controls; Surgery; Kirurgi;

    Abstract : Background: Worldwide, about 300 million people have some kind of visual impairment (VI). Most people with VI are in the older age range, as visual deficits increase with age. It is not unusual that people with VI suffer both from neck pain or scapular area symptoms and reduced balance, which they consider to be symptoms of old age. READ MORE