Search for dissertations about: "age related macular dissertation"

Found 5 swedish dissertations containing the words age related macular dissertation.

  2. 1. Evaluation of different macular degenerations. Function, morphology and clinical outcomes

    Author : Marion Silvia Schroeder; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Age-related macular degeneration; ABCA4-associated retinal degeneration; Electroretinography; Anti-VEGF; Swedish Macula Registry;

    Abstract : .... READ MORE

  4. 2. Novel endogenous mechanisms of complement regulation - A delicate balance

    Author : Andreas Holmér; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; short leucine rich glycoprotein; factor H; C1q; age-related macular degeneration; C4b-binding protein; prion disease; prion protein; Complement regulation; C-reactive protein;

    Abstract : In this thesis, the biochemical mechanisms for complement activation by endogenous proteins are explored. The short leucine-rich repeat proteins (SLRPs) help organise extracellular matrices. We found that several SLRPs bind C1q and of these, fibromodulin and osteoadherin trigger complement. READ MORE

  5. 3. Electrophysiology, Optical Coherence Tomography and Molecular Genetic Analysis in Patients with Glaucoma and/or Best Vitelliform Macular Dystrophy as Part of Clinical Care

    Author : Elisabeth Wittström; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glaucoma; BVMD; BEST1; full-field ERG; mfERG; OCT;

    Abstract : Glaucoma is a common ophthalmic disease with multifactorial aetiology. There is growing evidence that glaucoma is a disease of the entire retina and not only the inner retina. READ MORE

  6. 4. Retinal function in deaf-blind syndromes

    Author : Eva Malm; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; general anesthesia.; molecular genetics; hearing impairment; full-field electroretinography; Retinal degeneration;

    Abstract : A variety of disorders can cause retinal degeneration and hearing impairment, and it is of great value to have an early diagnosis since there is a large variation in phenotype and prognosis both within and between the different disorders. The general aim of this thesis was to characterize the retinal function, to describe the phenotype, and – where appropriate – to relate the phenotype to genotype in patients with combined visual and hearing impairment. READ MORE

  7. 5. Effect of Drugs on Rabbit Retina

    Author : Anna Cardiakidis Myers; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug toxicity; electroretinography; histopathology; intravitreal injection; rifabutin; anti-VEGF; triamcinolone; benzyl alcohol; anti-TNF-alpha; adalimumab;

    Abstract : The adverse effects of drugs in the eye are not easily detected, and the underlying pathogenesis not fully understood. The effects of four different kinds of drugs have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. READ MORE