Search for dissertations about: "age-related macular degeneration"

Showing result 6 - 10 of 31 swedish dissertations containing the words age-related macular degeneration.

  2. 6. Evaluation of different macular degenerations. Function, morphology and clinical outcomes

    Author : Marion Silvia Schroeder; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Age-related macular degeneration; ABCA4-associated retinal degeneration; Electroretinography; Anti-VEGF; Swedish Macula Registry;

    Abstract : .... READ MORE

  4. 7. Novel endogenous mechanisms of complement regulation - A delicate balance

    Author : Andreas Holmér; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; short leucine rich glycoprotein; factor H; C1q; age-related macular degeneration; C4b-binding protein; prion disease; prion protein; Complement regulation; C-reactive protein;

    Abstract : In this thesis, the biochemical mechanisms for complement activation by endogenous proteins are explored. The short leucine-rich repeat proteins (SLRPs) help organise extracellular matrices. We found that several SLRPs bind C1q and of these, fibromodulin and osteoadherin trigger complement. READ MORE

  5. 8. Safety and  efficacy in the cataract surgery process

    Author : Inger Westborg; Eva Mönestam; Marie Burstedt; Patrik Danielson; Björn Johansson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cataract; prospective cohort study; patient safety; age-related macular degeneration; Ophtalmology; oftalmiatrik;

    Abstract : BackgroundCataract and age-related macular degeneration (AMD) are two major causes for visual impairment in the elderly. Cataract surgery is one of the most common surgical interventions performed in the western world. As a consequence of the increasing number of operations performed, postoperative visits are a large workload for surgical units. READ MORE

  6. 9. Developmental insights and biomedical potential of human embryonic stem cells : modelling trophoblast differentiation and establishing novel cell therapies for age-related macular degeneration

    Author : Álvaro Plaza Reyes; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Understanding the molecular pathways responsible for lineage segregation in the preimplantation human embryo is critical in order to fully elucidate the mechanisms involved in pluripotency and differentiation of embryonic stem cells. A significant increase in our comprehension of such processes will lead to an improvement in the quality and efficiency of these cells for applications requiring stem cell maintenance and differentiation, such as regenerative medicine. READ MORE

  7. 10. Analysis of the Gene and Protein Causing Best Macular Dystrophy

    Author : Benjamin Bakall; Catharina Larsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; VMD2; bestrophin; macular degenration; mutation analysis; Genetik; Clinical genetics; Klinisk genetik; Clinical Genetics; klinisk genetik;

    Abstract : Best macular dystrophy (BMD) is an autosomal dominant inherited eye disease with a juvenile onset. Accumulation of the pigment lipofuscin in the retinal pigment epithelium can later cause macular degeneration and loss of vision. READ MORE