Search for dissertations about: "aggregation effects"

Showing result 1 - 5 of 234 swedish dissertations containing the words aggregation effects.

  2. 1. On the molecular mechanisms of the amyloid β-peptide aggregation

    Author : Kalyani Sanagavarapu; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein aggregation; amyloid β-peptide; aggregation kinetics; aggregation mechanism N-terminus; mutations; variants; sequence determinants; ; cross-seeding;

    Abstract : The pathogenesis of Alzheimer’s disease is widely believed to be due to production and deposition of the amyloid β-peptide. Several variants of the Aβ peptide are known to exist in in vivo. Variations include mutations or additional functional groups attached to residue side chains and may affect the aggregation process. READ MORE

  4. 2. Pathogenic effects of alpha-synuclein: modifications and toxicity

    Author : Natalie Landeck; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Keywords : Parkinson s disease; adeno-associated viral vector; animal models; alpha-synuclein; substantia nigra; dopaminergic neurons; phosphorylation; aggregation; toxicity;

    Abstract : Accumulation of intraneuronal inclusions, containing mainly a protein called alpha-synuclein (asyn), is thought to play a critical role in neurodegenerative disorders such as Parkinson's disease (PD). In these so called Lewy bodies, the majority of asyn is phosphorylated at serine 129 (pS129) suggesting that post-translational modifications may play a critical role in the process of aggregate formation. READ MORE

  5. 3. Micro-by-micro interactions : Aggregation dynamics, biofilms, and ecotoxicological impacts of suspended solids

    Author : Sophia Reichelt; Elena Gorokhova; Rehab El Shehawy; Julien Gigault; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; suspended solids; microplastics; bacteria; biofilm; aggregation; ecotoxicology; microalgae; Environmental Sciences; miljövetenskap;

    Abstract : Increasing concerns arise regarding the environmental risk of microplastics (MP) and their interactions with biota, prompting numerous effect studies. However, current ecotoxicology methods fall short when it comes to assessing MP impacts. READ MORE

  6. 4. Theoretical study on nonlinearoptical properties of organicchromophores in solutions

    Author : Ke Zhao; Yi Luo; Ruth Pachter; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; two-photon absorption; solvent effects; aggregation effects; molecular dynamics simulation; Theoretical chemistry; Teoretisk kemi;

    Abstract : Inter-molecular interactions have significant influences on linear and nonlinear optical properties of molecules including one- and two-photon absorptions, emissions, and various high order nonlinear polarizations. The related investigation has become an active and challenging research area. READ MORE

  7. 5. Congestion Charging in Urban Networks : Modelling Issues and Simulated Effects

    Author : Ida Kristoffersson; Leonid Engelson; Otto Anker Nielsen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Transport Modelling; Congestion Charging; Departure Time Choice; Dynamic Traffic Simulation; Welfare Effects; Equity;

    Abstract : One of the major challenges cities face today, in their development towards sustainable urban areas, is the need for an efficient and environmentally friendly transport system. This transport system should manage to tie together the city without strong adverse impact on urban environment, air-quality and climate change. READ MORE