Search for dissertations about: "agonism"

Showing result 1 - 5 of 28 swedish dissertations containing the word agonism.

  2. 1. Dopamine D2 and D3 receptors. Studies on transduction mechanisms and on the role of a D3 gene polymorphism

    Author : Monika Hellstrand; Göteborgs universitet; []
    Keywords : dopamine; dopamine D2 receptor; dopamine D3 receptor; transduction; CHO cells; partial agonism; inverse agonism; arachidonic acid; prostaglandin E2; cAMP; haloperidol; -3-PPP; PNU-99194A; polymorphism; personality;

    Abstract : The neurotransmitter dopamine has been implicated in the pathophysiology of, e.g., Parkinson s disease and schizophrenia, and dopamine receptor-active compounds are commonly employed therapeutically in these and other disorders. READ MORE

  4. 2. Radical democracy redux : politics and subjectivity beyond Habermas and Mouffe

    Author : Katarzyna Jezierska; Mats Lindberg; Mikael Carleheden; Aletta Norval; Örebro universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; radicaldemocracy; JürgenHabermas; ChantalMouffe; deliberative; agonistic; consensus; conflict; antagonism; agonism; subjectivity; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; Political science; Statsvetenskap; Political Science; Statskunskap;

    Abstract : This thesis investigates two contemporary theories of radical democracy, Jürgen Habermas’s deliberative and Chantal Mouffe’s agonistic democracy. By bringing the two scholars together and constructing a debate between them, their respective strengths and weaknesses are highlighted and the similarities and differences are pointed out. READ MORE

  5. 3. Metabolic and endocrine effects of SGLT2 inhibition

    Author : Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; Uppsala universitet; []
    Keywords : SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

    Abstract : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. READ MORE

  6. 4. Topics in multifractal measures, nonparametrics and biostatistics

    Author : Attila Frigyesi; Anestesiologi och intensivvård; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; confidence interval; mixed effects; Statistics; operations research; programming; actuarial mathematics; Statistik; operationsanalys; programmering; aktuariematematik; operational model of pharmacological agonism; concentration-response curves; dose-response curves; ventilation perfusion scintigraphy; V Q-scan; pulmonary embolism; automated method; box counting; correlation dimension; Hentschel-Procaccia dimension; Rényi dimension; generalized dimensions; fractal dimension estimation; dimension spectrum; multifractal measures; kernel density estimates; absolute continuity; singular distribution functions;

    Abstract : This thesis consists of four papers. The first two papers, which comprise the main part of the thesis, deal with an unexpected connection between kernel density estimators and dimension spectra for multifractal measures. READ MORE

  7. 5. OXYTOCIN AND VASOPRESSIN IN UTERINE ACTIVITY. Receptor-mediated agonism and antagonism with special regard to the aetiology and treatment of preterm labour and primary dysmenorrhoea

    Author : Thomas Bossmar; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; primary dysmenorrhoea.; preterm labour; vasopressin antagonist; receptors; oxytocin antagonist; vasopressin; Oxytocin; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : With a view to the aetiology and treatment of preterm labour and primary dysmenorrhoea we studied the influence of sexual steroids on the plasma levels of oxytocin and vasopressin, effect of these peptides on uterine contractility in vitro and in vivo, receptor concentrations and antagonists to oxytocin and vasopressin. In postmenopausal women oestrogen increased the concentrations in plasma of both peptides, whereas progesterone increased oxytocin but decreased vasopressin levels. READ MORE