Search for dissertations about: "airway hyperresponsiveness"

Showing result 1 - 5 of 33 swedish dissertations containing the words airway hyperresponsiveness.

  1. 1. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

    Author : Yaping Zhang; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

    Abstract : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. READ MORE

  2. 2. Airway responsiveness and exhaled nitric oxide : Studies in asthma and Sjögren's syndrome

    Author : Dóra Lúðvíksdóttir; Uppsala universitet; []
    Keywords : Medical sciences; Airway hyperresponsiveness; nitric oxide; airway inflammation; Sjögren s syndrome; asthma; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : In this thesis, four different types of provocation agents: methacholine, adenosine, cold air and mannitol were used to study different aspects of the airway responsiveness profile in asthma and Sjögren's syndrome. Exhaled nitric oxide (NO) and markers of eosinophil activation, serum eosinophil peroxidase (S-EPO) and eosinophil cationic protein (S-ECP) were measured. READ MORE

  3. 3. IgE sensitization against food allergens : Natural history, relation to airway inflammation and asthma

    Author : Antonios Patelis; Andrei Malinovschi; Eva Rönmark; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergen components; extract-based; exhaled NO; airway hyperresponsiveness; blood eosinophil count; IgE sensitization; food hypersensitivity; food allergens; perennial allergens; natural history; markers of systemic inflammation; markers of local inflammation; Lungmedicin; Lung Medicine; Fysiologi; Physiology; Immunologi; Immunology;

    Abstract : Background: According to recent studies in children, IgE sensitization not only against perennial allergens, but also against food allergens, is related to asthma risk and increased airway inflammation. During the last decade, a new technique for IgE determination based on allergen components has become available, but its use in epidemiological studies has been limited. READ MORE

  4. 4. From sneeze to wheeze: Non-invasive studies on asthma and rhinitis

    Author : David Aronsson; Lund Lungmedicin och Allergologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway inflammation; united airways; airway hyperresponsiveness; asthma; allergíc rhinitis;

    Abstract : Asthma and allergic rhinitis are diseases that cause major disability and illness in all ethnic groups and ages. It is well established that allergic rhinitis and asthma are closely linked entities and more than 75 % of the patients with asthma reports concomitant rhinitis. READ MORE

  5. 5. Airway effects of diesel exhaust in healthy and asthmatic subjects

    Author : Charlotta Nordenhäll; Thomas Sandström; Ellinor Ädelroth; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; diesel exhaust; airway responsiveness; airway inflammation; lung function; asthmatics; immunohistochemistry; bronchial epithelium;

    Abstract : Several epidemiological studies have revealed an association between particulate matter (PM) pollution and various health effects. Importantly, there is evidence to suggest that individuals with pre-existing respiratory disease, such as asthma, are more sensitive to elevated ground levels of particulate matter as compared to healthy subjects. READ MORE