Search for dissertations about: "airway reactivity"

Showing result 11 - 15 of 22 swedish dissertations containing the words airway reactivity.

2. 11. An experimental study of mediators in allergic bronchoconstriction with focus on eicosanoids

   Author : Ewa Selg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Leukotrienes; prostaglandins; histamine; guinea pig lung; ovalbumin; mast cell; cyclooxygenase; airway smooth muscle; COX inhibitors; NSAIDs;

   Abstract : Mast cells have a central role in the inflammatory response in airways of both atopic and non-atopic asthmatics. The mast cell-derived mediators such as histamine, leukotriene C4 and prostaglandin D2, released upon activation of the cell, produce acute bronchoconstriction that is characteristic of the early asthmatic response (EAR), and contribute to the development of airway inflammation and hyperresponsiveness following the initial reaction. READ MORE

4. 12. Pathogenesis and treatment of chemical-induced lung injury

   Author : Elisabeth Wigenstam; Anders Bucht; Thomas Sandström; Kjell Larsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemical-induced lung injury; dexamethasone; melphalan; vitamin E; respiratory mechanics; lungmedicin; Lung Medicine;

   Abstract : Inhalation of chemical substances can cause irritation to airways and in high doses acute airway injury. When mice are exposed to the alkylating nitrogen mustard analogue melphalan they develop an acute airway inflammation with a rapid influx of neutrophils to the lungs. READ MORE

5. 13. Mast cell activation in response to osmotic and immunological stimulation with focus on release of eicosanoid mediators

   Author : Magdalena Gulliksson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Exercise-induced bronchoconstriction; cyclooxygenase; cord blood derived mast cells; mannitol; prostaglandin D2; leukotriene C4; leukotriene E4; histamine and 15-lipoxygenase.;

   Abstract : Mast cells are important in asthma and other inflammatory diseases. Subjects with asthma have been found to have an increased number of mast cells in their airway smooth muscle and this was related to airway sensitivity. READ MORE

6. 14. The role of nitric oxide in porcine models of asthma and acute lung injury

   Author : Roelinde Middelveld; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Nitric oxide (NO) is a modulator of many important physiological processes in the body. It is produced endogenously in several cell types by a family of NO synthases (NOS). READ MORE

7. 15. Rehabilitation of adults with asthma : A quantitative and qualitative study

   Author : Margareta Emtner; Uppsala universitet; []
   Keywords : Medical sciences; Bronchial asthma; rehabilitation; exercise therapy; physical therapy; patient education; exercise-induced asthma; patient compliance; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; lungmedicin; Lung Medicine;

   Abstract : The general aim of this study was to evaluate the objective and subjective effects of a comprehensive rehabilitation program for adult asthmatic patients. A combination of quantitative and qualitative methods was used. READ MORE