Search for dissertations about: "airway remodeling"

Showing result 11 - 15 of 19 swedish dissertations containing the words airway remodeling.

  2. 11. Studies on neurotrophins in inflammatory pulmonary diseases

    Author : Charlotta Dagnell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma, sarcoidosis and chronic obstructive pulmonary disease (COPD) are inflammatory pulmonary diseases, all being characterized by tissue inflammation, tissue damage (airway remodeling) and loss of lung function. In order to increase possibilities to find new biomarkers, drug targets and better treatment options for the patients, further research on the underlying mechanisms driving the inflammation and airway remodeling in these diseases are required. READ MORE

  4. 12. Targeting the IL-33/ST2 pathway in asthma : implications for development, exacerbation and treatment

    Author : Anna Zoltowska Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma is a term that encompasses a disease spectrum with different phenotypes that vary in severity and whose common characteristic is airflow limitation. Allergic asthma is the most common phenotype of asthma and is characterized by allergen induced inflammatory responses, airway hyperresponsiveness (AHR), and remodeling. READ MORE

  5. 13. Fibroblasts as matrix modulating cells in asthma and COPD

    Author : Kristian Nihlberg; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Chronic lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are two lung diseases that are continuously increasing worldwide. Despite extensively research to find curative treatment, no so such therapy exists today. READ MORE

  6. 14. Investigating problematic severe asthma in children : a translational approach

    Author : Jon R Konradsen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Children with problematic severe asthma (PA) have persistent symptoms and/or severe exacerbations despite treatment with high doses of currently available asthma medications. The term PA includes children who are difficult to treat due to unidentified exacerbating factors (e.g. READ MORE

  7. 15. Viral wheeze and risk factors for childhood asthma : an evaluation of clinical, immunological and genetic factors

    Author : Katarina Stenberg Hammar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : It’s not fully understood why some children wheeze with viral infections, and why some develop severe asthma. In this study we compared two study groups; children presenting with acute wheeze (AW) before the age of four and age-matched healthy controls (HC), and we investigated factors that might contribute to increased vulnerability for airway infections and risk of later asthma development. READ MORE